Asymmetric α-alkylation of α,β-unsaturated esters.: Application to the synthesis of (R)-lavandulol, (R)-sesquilavandulol and related trifluoromethyl compounds

被引：0

作者：

Faure, S ^{[1
]}

Piva, O ^{[1
]}

机构：

[1] Univ Reims, CNRS, UMR 6519, UFR Sci, F-51687 Reims, France

来源：

SYNLETT | 1998年 / 12期

关键词：

lavandulol; sesquilavandulol; asymmetric alkylation; diacetone D-glucose; trifluoromethyl compounds;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diastereoselective alpha-alkylation/deconjugation of esters of diacetone D-glucose has been performed and applied to the syntheses of (R)-lavandulol, (R)-sesquilavandulol with de up to 74%. The same reaction performed with trifluoromethyl derivatives was also achieved but without significant diastereoselectivity.

引用

页码：1414 / 1416

页数：3

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