Evaluation of predictive biomarkers and resistance mechanisms of PI3K pathway inhibition in head and neck squamous cell carcinoma

被引：0
|
作者：
Mazumdar, Tuhina [1 ]
Byers, Lauren A. [1 ]
Ng, Patrick [1 ]
Mills, Gordon B. [1 ]
Peng, Shaohua [1 ]
Diao, Lixia [1 ]
Fan, Youhong [1 ]
Stemke-Hale, Katherine [1 ]
Heymach, John V. [1 ]
Myers, Jeffrey N. [1 ]
Glisson, Bonnie S. [1 ]
Johnson, Faye M. [1 ]
机构：
[1] UT MD Anderson Canc Ctr, Houston, TX USA
来源：
CANCER RESEARCH | 2014年 / 74卷 / 19期
关键词：
D O I：
10.1158/1538-7445.AM2014-903
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
903
引用
收藏
页数：1
相关论文
共 50 条
  • [1] A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell Carcinoma
    Mazumdar, Tuhina
    Byers, Lauren A.
    Ng, Patrick Kwok Shing
    Mills, Gordon B.
    Peng, Shaohua
    Diao, Lixia
    Fan, You-Hong
    Stemke-Hale, Katherine
    Heymach, John V.
    Myers, Jeffrey N.
    Glisson, Bonnie S.
    Johnson, Faye M.
    MOLECULAR CANCER THERAPEUTICS, 2014, 13 (11) : 2738 - 2750
  • [2] PI3K Inhibition for Squamous Cell Head and Neck Carcinoma
    Desilets, Antoine
    Soulieres, Denis
    CANCER JOURNAL, 2022, 28 (05): : 369 - 376
  • [3] INVESTIGATING MECHANISMS OF PI3K INHIBITOR RESISTANCE IN HEAD AND NECK SQUAMOUS CELL CARCINOMA
    Vien, M.
    Young, C. D.
    Wang, X.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2018, 66 (01) : 110 - 110
  • [4] Aurora kinases mediate resistance to PI3K inhibition in head and neck squamous cell carcinoma
    Sambandam, V.
    Mazumdar, T.
    Shen, L.
    Zhao, H.
    Peng, S.
    Wang, J.
    Johnson, F. M.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2020, 106 (05): : 1184 - 1184
  • [5] Targeting the PI3K/AKT/mTOR pathway in squamous cell carcinoma of the head and neck
    Simpson, Daniel R.
    Mell, Loren K.
    Cohen, Ezra E. W.
    ORAL ONCOLOGY, 2015, 51 (04) : 291 - 298
  • [6] Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma
    Cai, Yi
    Dodhia, Sonam
    Su, Gloria H.
    ONCOTARGET, 2017, 8 (13) : 22203 - 22217
  • [7] Pharmacological PI3K inhibition in head and neck squamous cell carcinoma: A systematic review
    Alves, L. B.
    Moura, A. C.
    dos Santos, J. Amorim
    Borges, G. A.
    Guerra, E. N. S.
    TOXICOLOGY IN VITRO, 2023, 88
  • [8] RAS/PI3K Crosstalk and Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma
    Rampias, T.
    Giagini, A.
    Siolos, S.
    Matsuzaki, H.
    Sasaki, C.
    Scorilas, A.
    Psyrri, A.
    CLINICAL CANCER RESEARCH, 2014, 20 (11) : 2933 - 2946
  • [9] Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma
    Bernard, Monique
    Cardin, Guillaume B.
    Cahuzac, Maxime
    Ayad, Tareck
    Bissada, Eric
    Guertin, Louis
    Bahig, Houda
    Nguyen-Tan, Phuc Felix
    Filion, Edith
    Ballivy, Olivier
    Soulieres, Denis
    Rodier, Francis
    Christopoulos, Apostolos
    CANCERS, 2020, 12 (09) : 1 - 24
  • [10] Sustained Aurora Kinase B Expression Confers Resistance to PI3K Inhibition in Head and Neck Squamous Cell Carcinoma
    Shah, Pooja A.
    Sambandam, Vaishnavi
    Fernandez, Anne M.
    Zhao, Hongyun
    Mazumdar, Tuhina
    Shen, Li
    Wang, Qi
    Ahmed, Kazi M.
    Ghosh, Soma
    Frederick, Mitchell J.
    Wang, Jing
    Johnson, Faye M.
    CANCER RESEARCH, 2022, 82 (23) : 4444 - 4456
12345