Natalizumab therapy of multiple sclerosis: recommendations of the Multiple Sclerosis Study Group-Italian Neurological Society

被引：15

作者：

Ghezzi, A. ^{[1
]}

Grimaldi, L. M. E. ^{[2
]}

Marrosu, M. G. ^{[3
]}

Pozzilli, C. ^{[4
]}

Comi, G. ^{[5
]}

Bertolotto, A. ^{[6
,28
]}

Trojano, M. ^{[7
]}

Gallo, P. ^{[8
]}

Capra, R. ^{[9
]}

Centonze, D. ^{[10
]}

Millefiorini, E. ^{[11
]}

Sotgiu, S. ^{[12
]}

Morra, V. Brescia ^{[13
]}

Amato, M. P. ^{[14
]}

Lugaresi, A. ^{[15
]}

Mancardi, G. ^{[16
]}

Caputo, D. ^{[17
]}

Montanari, E. ^{[18
]}

Provinciali, L. ^{[19
]}

Durelli, L. ^{[20
]}

Bergamaschi, R. ^{[21
]}

Bellantonio, P. ^{[22
]}

Tola, M. R. ^{[23
]}

Cottone, S. ^{[24
]}

Savettieri, G. ^{[25
]}

Tedeschi, G. ^{[26
,27
]}

机构：

[1] Osped Gallarate, Ctr Studi Sclerosi Multipla, UO Neurol 2, Gallarate, Italy

[2] Fdn Ist San Raffaele G Giglio, UO Neurol, Palermo, Italy

[3] Univ Cagliari, Ctr Sclerosi Multipla & Clin Neurol, Cagliari, Italy

[4] Univ Roma La Sapienza, Osped S Andrea, Ctr Sclerosi Multipla, Rome, Italy

[5] Univ Milan, Osped San Raffaele, Dipartimento Neurol, Ist Sci Univ, I-20127 Milan, Italy

[6] AOUS Luigi Gonzaga, Ctr Riferimento Reg Sclerosi Multipla CRESM, Turin, Italy

[7] Policlin Univ Bari, Dipartimento Sci Neurol & Psichiat, Bari, Italy

[8] AO Univ Padova, Ctr Riferimento Reg Sclerosi Multipla, Padua, Italy

[9] Spedali Civil Brescia, Ctr Riferimento Sclerosi Multipla, USD Neurol, I-25125 Brescia, Italy

[10] Univ Roma Tor Vergata, Dipartimento Neurosci, Neurol Clin, Rome, Italy

[11] Univ Roma La Sapienza, Dipartimento Sci Neurol, Cattedra Clin Neurol 3, I-00185 Rome, Italy

[12] Univ Sassari, Ist Clin Neurol, I-07100 Sassari, Italy

[13] Univ Naples Federico II, Dipartimento Sci Neurol, Naples, Italy

[14] Univ Florence, Dipartimento Sci Neurol & Psichiat, Clin Neurol 1, Florence, Italy

[15] Univ G dAnnunzio, Dipartimento Neurosci & Immagini, Chieti, Italy

[16] Univ Genoa, Neurol Clin 2, Dipartimento Neurosci Oftalmol & Genet, Genoa, Italy

[17] Ctr IRCCS S Maria Nascente Fdn Don Gnocchi, Milan, Italy

[18] Univ Parma, Neurol Clin, UO Neurol, I-43100 Parma, Italy

[19] Univ Politecn Marche, AOU Osped Riuniti, Neurol Clin, Ancona, Italy

[20] Osped S Luigi Gonzaga, Div Neurol, Turin, Italy

[21] IRCCS Fdn Ist Neurol Nazl C Mondino, Ctr Sclerosi Multipla, Pavia, Italy

[22] Ctr Sclerosi Multipla IRCCS Neuromed, Dipartimento Neurol, Pozzilli, Isernia, Italy

[23] AOU Arcispedale St Anna, UO Neurol, Dipartimento Neurosci Riabilitaz, Ferrara, Italy

[24] AO Villa Sofia CTO, UO Neurol, Palermo, Italy

[25] Univ Palermo, Dipartimento Univ Neurosci Clin, Palermo, Italy

[26] Univ Naples 2, Dipartimento Sci Neurol, Naples, Italy

[27] Ist Hermitage Capodimonte, Naples, Italy

[28] AOUS Luigi Gonzaga, Neurobiol Clin, Turin, Italy

来源：

NEUROLOGICAL SCIENCES | 2011年 / 32卷 / 02期

关键词：

Multiple sclerosis; Natalizumab; PML; IRIS; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; EFFICACY; DISEASE; SAFETY;

D O I：

10.1007/s10072-010-0469-0

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Three years after the introduction of natalizumab (NA) therapy for the second line treatment of relapsing-remitting multiple sclerosis (MS), Italian MS centers critically reviewed the scientific literature and their own clinical experience. Natalizumab was shown to be highly efficaciuos in the treatment of MS. However, the risk of progressive multifocal leukoencephalopathy was confirmed and defined better. This article summarizes the MS-SIN Study Group recommendations on the use of NA in MS, with particular reference to the appropriate selection and monitoring of patients as well as to the management of adverse events.

引用

页码：351 / 358

页数：8

共 50 条

[1] Natalizumab therapy of multiple sclerosis: recommendations of the Multiple Sclerosis Study Group—Italian Neurological Society
A. Ghezzi
L. M. E. Grimaldi
M. G. Marrosu
C. Pozzilli
G. Comi
A. Bertolotto
M. Trojano
P. Gallo
R. Capra
D. Centonze
E. Millefiorini
S. Sotgiu
V. Brescia Morra
M. P. Amato
A. Lugaresi
G. Mancardi
D. Caputo
E. Montanari
L. Provinciali
L. Durelli
R. Bergamaschi
P. Bellantonio
M. R. Tola
S. Cottone
G. Savettieri
G. Tedeschi
Neurological Sciences, 2011, 32 : 351 - 358
[2] Recommendations for the management of urinary disorders in multiple sclerosis: a consensus of the Italian Multiple Sclerosis Study Group
A. Ghezzi
R. Carone
G. Del Popolo
M. P. Amato
A. Bertolotto
M. Comola
U. Del Carro
P. Di Benedetto
A. Giannantoni
M. L. Lopes de Carvalho
E. Montanari
F. Patti
A. Protti
S. Rasia
A. Salonia
C. Scandellari
F. Sperli
M. Spinelli
C. Solaro
A. Uccelli
M. Zaffaroni
V. Zipoli
Neurological Sciences, 2011, 32 : 1223 - 1231
[3] Recommendations for the management of urinary disorders in multiple sclerosis: a consensus of the Italian Multiple Sclerosis Study Group
Ghezzi, A.
Carone, R.
Del Popolo, G.
Amato, M. P.
Bertolotto, A.
Comola, M.
Del Carro, U.
Di Benedetto, P.
Giannantoni, A.
de Carvalho, M. L. Lopes
Montanari, E.
Patti, F.
Protti, A.
Rasia, S.
Salonia, A.
Scandellari, C.
Sperli, F.
Spinelli, M.
Solaro, C.
Uccelli, A.
Zaffaroni, M.
Zipoli, V.
NEUROLOGICAL SCIENCES, 2011, 32 (06) : 1223 - 1231
[4] Disease-modifying therapy in multiple sclerosis: recommendations of Multiple Sclerosis and Neuroimmunology Section of Polish Neurological Society
Kulakowska, Alina
Mirowska-Guzel, Dagmara
Kalinowska, Alicja
Bartosik-Psujek, Halina
Brola, Waldemar
Stasiolek, Mariusz
Glabinski, Andrzej
Losy, Jacek
Potemkowski, Andrzej
Rejdak, Konrad
Sarzynska-Dlugosz, Iwona
Siger, Malgorzata
Stepien, Adam
Wawrzyniak, Slawomir
Zaborski, Jacek
Zakrzewska-Pniewska, Beata
Adamczyk-Sowa, Monika
NEUROLOGIA I NEUROCHIRURGIA POLSKA, 2024, 58 (06) : 569 - 585
[5] Natalizumab therapy of multiple sclerosis
Hutchinson, Michael
CYTOKINE, 2009, 48 (1-2) : 22 - 22
[6] Natalizumab Therapy for Multiple Sclerosis
Jeremy Chataway
David H. Miller
Neurotherapeutics, 2013, 10 : 19 - 28
[7] Natalizumab Therapy of Multiple Sclerosis
Hutchinson, Michael
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 2010, 30 (10): : 787 - 789
[8] Natalizumab Therapy for Multiple Sclerosis
Chataway, Jeremy
Miller, David H.
NEUROTHERAPEUTICS, 2013, 10 (01) : 19 - 28
[9] Natalizumab therapy in multiple sclerosis
Stueve, O.
MULTIPLE SCLEROSIS, 2007, 13 (09): : 1210 - 1210
[10] Natalizumab Therapy for Multiple Sclerosis
Derfuss, Tobias
Kuhle, Jens
Lindberg, Raija
Kappos, Ludwig
SEMINARS IN NEUROLOGY, 2013, 33 (01) : 26 - 36

← 1 2 3 4 5 →