Catalytic Synthesis of Substituted Indoles and Quinolines from the Dehydrative C-H Coupling of Arylamines with 1,2-and 1,3-Diols

被引：22
|
作者：
Lee, Hanbin [1 ]
Yi, Chae S. [1 ]
机构：
[1] Marquette Univ, Dept Chem, Milwaukee, WI 53201 USA
来源：
ORGANOMETALLICS | 2016年 / 35卷 / 11期
基金：
美国国家科学基金会;
关键词：
ENANTIOSELECTIVE KETONE HYDROGENATION; LIGAND BIFUNCTIONAL ADDITION; AMINE EXCHANGE-REACTION; N-N BOND; RUTHENIUM COMPLEX; INTERNAL ALKYNES; OXIDATIVE CYCLIZATION; CARBONYL-COMPOUNDS; HYDRIDE COMPLEX; ANILINES;
D O I：
10.1021/acs.organomet.6b00273
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The cationic ruthenium-hydride complex catalyzes the dehydrative C-H coupling reaction of arylamines with 1,2-diols to form the indole products. The analogous coupling of arylamines with 1,3-diols afforded the substituted, quinolines. The catalytic method directly forms these coupling products in a highly regioselective manner without generating any toxic byprodficts.
引用
收藏
页码：1973 / 1977
页数：5
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