Characterization of a Putative Hemagglutinin Gene in the Caprine Model for Brucellosis

被引：0

作者：

Perry, Quinesha L. ^{[1
]}

Hagius, Sue D. ^{[2
]}

Walker, Joel V. ^{[2
]}

Duhon, Lauren ^{[1
]}

Elzer, Philip H. ^{[1
,2
]}

机构：

[1] Louisiana State Univ, Sch Vet Med, Dept Pathobiol Sci, Baton Rouge, LA 70803 USA

[2] Louisiana State Univ, Ctr Agr, Dept Vet Sci, Baton Rouge, LA 70803 USA

来源：

EMERGING AND ENDEMIC PATHOGENS: ADVANCES IN SURVEILLANCE, DETECTION AND IDENTIFICATION | 2010年

关键词：

DELETION MUTANT; PLANT-PATHOGENS; MELITENSIS; 16M; PREGNANT GOATS; ABORTUS; VIRULENCE; MICE; IDENTIFICATION; SURVIVAL; GENOME;

D O I：

10.1007/978-90-481-9637-1_9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

With the completion of the genomic sequences of Brucella melitensis 16M and B. abortus 2308 and the vaccine strain RB51, a putative hemagglutinin gene was identified that is present in 16M and absent in B. abortus. The possibility of this hemagglutinin being a potential host specificity factor was evaluated via expression in trans in B. abortus 2308-QAE and RB51-QAE. Using the caprine brucellosis model, colonization and pathogenesis studies were performed to evaluate the strains.

引用

页码：99 / +

页数：4

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