POOLED GENOMIC SCREENS IDENTIFY ANTI-APOPTOTIC GENES AS MEDIATORS OF CHEMOTHERAPY RESISTANCE IN OVARIAN CANCER

被引:0
|
作者
Stover, Elizabeth H. [1 ,2 ,3 ]
Baco, Maria B. [3 ]
Cohen, Ofir [3 ]
Li, Yvonne [3 ]
Christie, Elizabeth [4 ]
Bagul, Mukta [3 ]
Goodale, Amy [3 ]
Lee, Yenarae [3 ]
Pantel, Sasha [3 ]
Rees, Matthew [3 ]
Wei, Guo [3 ]
Presser, Adam [6 ]
Zervantonakis, Ioannis [5 ]
Bhola, Patrick [1 ]
Ryan, Jeremy [1 ]
Guerriero, Jennifer [1 ]
Liang, Felice [3 ]
Cherniack, Andrew [3 ]
Piccioni, Federica [3 ]
Matulonis, Ursula A. [1 ,2 ]
Bowtell, David D. L. [4 ]
Letai, Anthony [2 ]
Sarosiek, Kris [6 ]
Garraway, Levi [7 ]
Johannessen, Cory M. [3 ]
Meyerson, Matthew [1 ,2 ,3 ]
机构
[1] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02215 USA
[2] Harvard Med Sch, Dept Med, Boston, MA 02115 USA
[3] Broad Inst MIT & Harvard, Canc Program, Cambridge, MA 02142 USA
[4] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
[5] Harvard Med Sch, Dept Cell Biol, Boston, MA 02115 USA
[6] Harvard TH Chan Sch Publ Hlth, Dept Environm Hlth, John B Little Ctr Radiat Sci, Boston, MA USA
[7] Eli Lilly & Co, Indianapolis, IN 46285 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:74 / 74
页数:1
相关论文
共 50 条
  • [1] Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer
    Stover, Elizabeth H.
    Baco, Maria B.
    Cohen, Ofir
    Li, Yvonne Y.
    Christie, Elizabeth L.
    Bagul, Mukta
    Goodale, Amy
    Lee, Yenarae
    Pantel, Sasha
    Rees, Matthew G.
    Wei, Guo
    Presser, Adam G.
    Gelbard, Maya K.
    Zhang, Weiqun
    Zervantonakis, Ioannis K.
    Bhola, Patrick D.
    Ryan, Jeremy
    Guerriero, Jennifer L.
    Montero, Joan
    Liang, Felice J.
    Cherniack, Andrew D.
    Piccioni, Federica
    Matulonis, Ursula A.
    Bowtell, David D. L.
    Sarosiek, Kristopher A.
    Letai, Anthony
    Garraway, Levi A.
    Johannessen, Cory M.
    Meyerson, Matthew
    MOLECULAR CANCER RESEARCH, 2019, 17 (11) : 2281 - 2293
  • [2] In vivo pooled shRNA library screens identify cancer genes driving epithelial ovarian cancer
    Kodama, Michiko
    Kodama, Takahiro
    Newberg, Justin
    Copeland, Neal G.
    Jenkins, Nancy A.
    CANCER RESEARCH, 2016, 76
  • [3] Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy
    Contreras, Jacob I.
    Robb, Caroline M.
    King, Hannah M.
    Baxter, Jared
    Crawford, Ayrianne J.
    Kour, Smit
    Kizhake, Smitha
    Sonawane, Yogesh A.
    Rana, Sandeep
    Hollingsworth, Michael A.
    Luo, Xu
    Natarajan, Amarnath
    ACS CHEMICAL BIOLOGY, 2018, 13 (05) : 1148 - 1152
  • [4] Anti-Apoptotic Mechanisms of Drug Resistance in Cancer
    Wilson, T. R.
    Johnston, P. G.
    Longley, D. B.
    CURRENT CANCER DRUG TARGETS, 2009, 9 (03) : 307 - 319
  • [5] Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer
    Zaffaroni, N
    Pennati, M
    Colella, G
    Perego, P
    Supino, R
    Gatti, L
    Pilotti, S
    Zunino, F
    Daidone, MG
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2002, 59 (08) : 1406 - 1412
  • [6] Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer
    N. Zaffaroni
    M. Pennati
    G. Colella
    P. Perego
    R. Supino
    L. Gatti
    S. Pilotti
    F. Zunino
    M. G. Daidone
    Cellular and Molecular Life Sciences CMLS, 2002, 59 : 1406 - 1412
  • [7] INTEGRATIVE GENOMIC AND TRANSCRIPTOMIC ANALYSIS TO IDENTIFY BIOMARKERS OF CHEMOTHERAPY RESISTANCE IN SEROUS EPITHELIAL OVARIAN CANCER
    Koti, M.
    Gooding, R. J.
    Nuin, P.
    Haslehurst, A.
    Weberpals, J.
    Childs, T.
    Bryson, P.
    Dharsee, M.
    Evans, K.
    Feilotter, H. E.
    Park, P.
    Squire, J. A.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2013, 23 (08)
  • [9] Inhibiting the inhibitors: Targeting anti-apoptotic proteins in cancer and therapy resistance
    Shahar, Nir
    Larisch, Sarit
    DRUG RESISTANCE UPDATES, 2020, 52
  • [10] Human ovarian cancer cell seeding density as a mechanism of cisplatin resistance associated with expression of anti-apoptotic and autophagy proteins
    Brown, Thomas W.
    Punyamurtula, Ujwal
    El-Deiry, Wafik S.
    CANCER RESEARCH, 2023, 83 (07)