Pushing the frontiers of density functionals by solving the fractional electron problem

被引：266

作者：

Kirkpatrick, James ^{[1
]}

McMorrow, Brendan ^{[1
]}

Turban, David H. P. ^{[1
]}

Gaunt, Alexander L. ^{[1
]}

Spencer, James S. ^{[1
]}

Matthews, Alexander G. D. G. ^{[1
]}

Obika, Annette ^{[1
]}

Thiry, Louis ^{[2
]}

Fortunato, Meire ^{[1
]}

Pfau, David ^{[1
]}

Castellanos, Lara Roman ^{[1
]}

Petersen, Stig ^{[1
]}

Nelson, Alexander W. R. ^{[1
]}

Kohli, Pushmeet ^{[1
]}

Mori-Sanchez, Paula ^{[3
,4
]}

Hassabis, Demis ^{[1
]}

Cohen, Aron J. ^{[1
,5
]}

机构：

[1] DeepMind, 6 Pancras Sq, London N1C 4AG, England

[2] PSL Univ, Dept Informat, CNRS, ENS, Paris, France

[3] UAM, Dept Quim, Madrid 28049, Spain

[4] UAM, IFIMAC, Madrid 28049, Spain

[5] Max Planck Inst Solid State Res, D-70569 Stuttgart, Germany

来源：

SCIENCE | 2021年 / 374卷 / 6573期

关键词：

GENERALIZED GRADIENT APPROXIMATION; MAIN-GROUP THERMOCHEMISTRY; NONCOVALENT INTERACTIONS; ATOMIZATION ENERGIES; KINETICS; HYBRID; DFT; OPTIMIZATION; MECHANISMS; STEPWISE;

D O I：

10.1126/science.abj6511

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Density functional theory describes matter at the quantum level, but all popular approximations suffer from systematic errors that arise from the violation of mathematical properties of the exact functional. We overcame this fundamental limitation by training a neural network on molecular data and on fictitious systems with fractional charge and spin. The resulting functional, DM21 (DeepMind 21), correctly describes typical examples of artificial charge delocalization and strong correlation and performs better than traditional functionals on thorough benchmarks for main-group atoms and molecules. DM21 accurately models complex systems such as hydrogen chains, charged DNA base pairs, and diradical transition states. More crucially for the field, because our methodology relies on data and constraints, which are continually improving, it represents a viable pathway toward the exact universal functional.

引用

页码：1385 / +

页数：50

共 73 条

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