共 50 条
- [1] Novel bone-targeted Src tyrosine kinase inhibitor drug discoveryCURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2003, 6 (05) : 729 - 741Shakespeare, WCMetcalf, CAWang, YHSundaramoorthi, RKeenan, TWeigele, MBohacek, RSDalgarno, DCSawyer, TK
- [2] A novel bone-targeted SRC tyrosine kinase inhibitor, AP23451, prevents bone loss in vitro and in vivoBONE, 2003, 32 (05) : S129 - S129Boyce, BFXing, LBain, SShen, VWang, YShakespeare, WMetcalf, CDalgarno, DIuliucci, JSawyer, T
- [3] Bone-targeted Src kinase inhibitors: Novel pyrrolo- and pyrazolopyrimidine analoguesBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (18) : 3063 - 3066Sundaramoorthi, RShakespeare, WCKeenan, TPMetcalf, CAWang, YHMani, UTaylor, MLiu, SYBohacek, RSNarula, SSDalgarno, DCvan Schravandijk, MRViolette, SMLiou, SAdams, SRam, MKKeats, JAWeigele, MSawyer, TK
- [4] Bone-targeted 2,6,9-trisubstituted purines: Novel inhibitors of Src tyrosine kinase for the treatment of bone diseasesBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (18) : 3067 - 3070Wang, YHMetcalf, CAShakespeare, WCSundaramoorthi, RKeenan, TPBohacek, RSvan Schravendijk, MRViolette, SMNarula, SSDalgarno, DCHaraldson, CKeats, JLiou, SMani, UPradeepan, SRam, MAdams, SWeigele, MSawyer, TK
- [5] Design and synthesis of novel bone-targeted SRC tyrosine kinase inhibitor drug discoveryABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 227 : U11 - U11Sundaramoorthi, RShakespeare, WCMetcalf, CAWang, KHLiu, SYBohacek, RSNarula, SSKeats, JAWardwell, SIuliucci, JWeigele, MDalgarno, DCSawyer, TK
- [6] Structure-based design of novel osteophilic therapeutics for bone diseases: Discovery of in vivo effective, bone-targeted SRC tyrosine kinase inhibitorsBIOPOLYMERS, 2003, 71 (03) : 296 - 296Sawyer, TKDalgarno, DBohacek, RShakespeare, WCMetcalf, CAWang, YSundaramoorthi, RKeenan, TNarula, SHatada, Mvan Schravendijk, MRIuliucci, JWeigele, MChorev, MAlexander, JRosenblatt, MBain, SShen, VXing, LBoyce, BF
- [7] Signal transduction pathways and bone diseases: Novel bone-targeted SRC kinase inhibitors with dual antiresorptive and bone anabolic properties.ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 227 : U71 - U71Wang, YHXing, LPMetcalf, CShakespeare, WSundaramoorthi, RBohacek, RNarula, SWardwell, SIuliucci, JWeigele, MDalgarno, DBoyce, BSawyer, T
- [8] Novel bone-targeted Src tyrosine kinase inhibitor drug discovery (vol 6, pg 729, 2002)CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2003, 6 (06) : 978 - 978Shakespeare, WCMetcalf, CAWang, YHSundaramoorthi, RKeenan, TWeigele, MBohacek, RSDalgarno, DCSawyer, TK
- [9] Bone-targeted pyrido[2,3-d]pyrimidin-7-ones:: Potent inhibitors of Src tyrosine kinase as novel antiresorptive agentsBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (18) : 3071 - 3074Vu, CBLuke, GPKawahata, NShakespeare, WCWang, YHSundaramoorthi, RMetcalf, CAKeenan, TPPradeepan, SCorpuz, EMerry, TBohacek, RSDalgarno, DCNarula, SSvan Schravendijk, MRRam, MKAdams, SLiou, SKeats, JAViolette, SMGuan, WWeigele, MSawyer, TK
- [10] Bone-targeted src kinase inhibitors: Novel pyrrolo- and pyrazolopyrimidine analogues (vol 13, pg 3063, 2003)BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (24) : 4519 - 4519Sundaramoorthi, RShakespeare, WCKeenan, TPMetcalf, CAWang, YHMani, UMerry, TLiu, SYBohacek, RSNarula, SSDalgarno, DCVan Schravendijk, MRViolette, SMLiou, SAdams, SRam, MKKeats, JAWeigle, MSawyer, TK