The influence of cytochrome P450-dependent arachidonic acid metabolites in regulation of the vascular tone

被引：0

作者：

Krzhechkovskaya, VV ^{[1
]}

Nebolsin, VE ^{[1
]}

Zheltukhina, GA ^{[1
]}

Evstigneeva, RP ^{[1
]}

Rubtsova, ER ^{[1
]}

机构：

[1] Lomonosov Moscow State Acad Fine Technol, Moscow, Russia

来源：

VOPROSY MEDITSINSKOI KHIMII | 1998年 / 44卷 / 05期

关键词：

arachidonic acid metabolites; cytochrome P450; vascular tone;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The present paper reviews recent studies about the role of the cytochrome P-450-dependent arachidonic acid metabolites. There metabolites take part in the regulation of the vascular tone. They are the intracellular messenger and play an integral role in the relation of the vascular endothelium and smooth muscle cells. The arachidonic acid metabolites regulate the activity of the ionic channels. It is demonstrated that derivatives of arachidonic acid have the role in the pathogenesis of hypertension.

引用

页码：417 / 422

页数：6

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