Polysaccharides from Chinese herbal medicine for anti-diabetes recent advances

被引：103

作者：

Zheng, Yu ^{[1
,2
]}

Bai, Lan ^{[3
,4
]}

Zhou, Yanping ^{[3
,4
]}

Tong, Rongsheng ^{[3
,4
]}

Zeng, Minghui ^{[5
]}

Li, Xiaofang ^{[1
,2
]}

Shi, Jianyou ^{[3
,4
]}

机构：

[1] Chengdu Univ Tradit Chinese Med, Key Lab Systemat Res Dev & Utilizat Chinese Med R, Key Lab Standardizat Chinese Herbal Med,Minist Ed, Key Lab Breeding Base Cofounded Sichuan Prov,Phar, Chengdu 611137, Sichuan, Peoples R China

[2] Minist Sci & Technol, Chengdu 611137, Sichuan, Peoples R China

[3] Univ Elect Sci & Technol China, Acad Med Sci, Sch Med, Personalized Drug Therapy Key Lab Sichuan Prov, Chengdu 610072, Sichuan, Peoples R China

[4] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Sch Med, Personalized Drug Therapy Key Lab Sichuan Prov, Chengdu 610072, Sichuan, Peoples R China

[5] Qionglai Municipal Med Ctr Hosp Sichuan Prov, Dept Pharm, Chengdu 611530, Sichuan, Peoples R China

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2019年 / 121卷

关键词：

Diabetes mellitus; Polysaccharides; Chinese herbal medicine; Mechanism; HIGH-FAT-DIET; GANODERMA-LUCIDUM POLYSACCHARIDES; LYCIUM-BARBARUM POLYSACCHARIDES; COPTIS-CHINENSIS POLYSACCHARIDE; VITRO HYPOGLYCEMIC ACTIVITIES; MULBERRY LEAF EXTRACT; ASTRAGALUS POLYSACCHARIDES; OPHIOPOGON-JAPONICUS; INSULIN-RESISTANCE; IN-VITRO;

D O I：

10.1016/j.ijbiomac.2018.10.072

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Diabetes mellitus (DM) is a chronic disease occurring when the body no longer produces adequate insulin or when it cannot use the produced insulin effectively. In recent years, more and more studies have revealed that Chinese materia medica polysaccharides are the key bioactive components of Chinese herbal medicine and have significant anti-diabetic effects with almost no side effects. In this review, we summarize 10 kinds of polysaccharides from Chinese herbal medicine which have effective anti-diabetes activities and the mechanism since 2014 to now. And it is hoped that this will provide an enlightenment for our researchers to design, research and development of polysaccharides. (C) 2018 Published by Elsevier B.V.

引用

页码：1240 / 1253

页数：14

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