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Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Guangdong Prov Key Lab Coronary Heart Dis Prevent, Dept Cardiol,Guangdong Cardiovasc Inst, Guangzhou 510100, Peoples R China Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Guangdong Prov Key Lab Coronary Heart Dis Prevent, Dept Cardiol,Guangdong Cardiovasc Inst, Guangzhou 510100, Peoples R China