Nickel catalyzed intramolecular oxidative coupling: synthesis of 3-aryl benzofurans

被引:4
|
作者
Aggarwal, Sakshi [1 ]
Srinivas, Dasari [1 ]
Sreenivasulu, Chinnabattigalla [1 ]
Satyanarayana, Gedu [1 ]
机构
[1] Indian Inst Technol, Dept Chem, Hyderabad 502285, Telangana, India
关键词
ONE-POT SYNTHESIS; MARINE SPONGE; BIOLOGICAL-ACTIVITY; EFFICIENT SYNTHESIS; TERMINAL ALKYNES; O-ALKYNYLPHENOLS; FACILE SYNTHESIS; ALKENYL PHENOLS; C-C; MICROWAVE;
D O I
10.1039/d0ra03071f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Recent research has been focused on the transition metal-catalyzed reactions. Herein we have developed nickel-catalyzed synthesis of 3-aryl benzofurans fromortho-alkenyl phenolsviaintramolecular dehydrogenative coupling. Notably, simple O(2)gas served as an oxidant, without using any sacrificial hydrogen acceptor. The strategy enabled the synthesis of 3-aryl benzofurans in good to excellent yields.
引用
收藏
页码:22264 / 22272
页数:9
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