Rhodium-Tellurium Nanorod Synthesis Using Galvanic Replacement-Polyol Regrowth for Thermo-Dynamic Dual-Modal Cancer Phototherapy

被引：9

作者：

Kang, Seounghun ^{[1
]}

Yim, Gyeonghye ^{[2
]}

Chae, Se-Youl ^{[1
]}

Kim, Subean ^{[2
]}

Gil, Yeong-Gyu ^{[2
]}

Kim, Young-Kwan ^{[3
]}

Min, Dal-Hee ^{[1
,4
]}

Jang, Hongje ^{[2
]}

机构：

[1] Seoul Natl Univ, Dept Chem, Seoul 08826, South Korea

[2] Kwangwoon Univ, Dept Chem, Seoul 01897, South Korea

[3] Dongguk Univ, Dept Chem, Seoul 04620, South Korea

[4] Lemonex Inc, Inst Biotherapeut Convergence Technol, Seoul 08826, South Korea

来源：

ACS APPLIED MATERIALS & INTERFACES | 2022年 / 14卷 / 36期

基金：

新加坡国家研究基金会;

关键词：

tellurium nanorod; rhodium nanoparticle; photothermal conversion; photocatalyst; galvanic replacement; NANOPARTICLES; RH; SIZE; NANOSTRUCTURES; CATALYSIS;

D O I：

10.1021/acsami.2c07281

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Rh is a noble metal introduced in bioapplications, including diagnosis and therapy, in addition to its consolidated utilization in organic catalysis and electrocatalysis. Herein, we designed the synthesis of highly crystalline Rh nanocrystal-decorated Rh-Te nanorods (RhTeNRs) through galvanic replacement of sacrificial Te nanorod (TeNR) templates and subsequent polyol regrowth. The obtained RhTeNRs showed excellent colloidal stability and efficient heat dissipation and photocatalytic activity under various laser irradiation wavelengths. Based on the confirmed biocompatibility, RhTeNRs were introduced into in vitro and in vivo cancer phototherapies. The results confirmed the selective physical death of cancer cells in the local area through laser irradiation. While chemotherapy does not guarantee successful treatment due to side effects and resistance, phototherapy using heat and reactive oxygen species generation of RhTeNRs induces physical death.

引用

页码：40513 / 40521

页数：9