A facile synthesis of new 3-substituted-2,3-dihydropyrido[3,2-d]pyrimidine-2,4-diones

被引:5
|
作者
Mamouni, R
Akssira, M
Aadil, M
Elhakmaoui, A
Lasri, J
Zaballos-Garcia, E
机构
[1] Univ Hassan II Mohammedia, Chim Bioorgan & Analyt Lab, Mohammadia 20650, Morocco
[2] Univ Valencia, Fac Farm, Dept Quim Organ, E-46010 Valencia, Spain
关键词
D O I
10.1081/SCC-120026855
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Pyrido[3,2-d]pyrimidine-2,4-diones derivatives have been synthesized in good yields by two efficient synthetic routes, the first one through an hetero-cyclization on the ureas derivatives 3a-e under alkaline conditions, the second one by condensation of the isocyanate 2 with various arylalkylamines in pyridine.
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页码:4259 / 4268
页数:10
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