Typhoid vaccine development with a human challenge model

被引:14
|
作者
Feasey, Nicholas A. [1 ]
Levine, Myron M. [2 ]
机构
[1] Univ Liverpool Liverpool Sch Trop Med, Dept Clin Sci, Liverpool L3 5QA, Merseyside, England
[2] Univ Maryland, Sch Med, Ctr Vaccine Dev, Baltimore, MD 21201 USA
来源
LANCET | 2017年 / 390卷 / 10111期
基金
英国惠康基金;
关键词
SALMONELLA-TYPHI;
D O I
10.1016/S0140-6736(17)32407-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2419 / 2421
页数:3
相关论文
共 50 条
  • [1] Typhoid epidemiology, diagnostics and the human challenge model
    Darton, Thomas C.
    Blohmke, Christoph J.
    Pollard, Andrew J.
    CURRENT OPINION IN GASTROENTEROLOGY, 2014, 30 (01) : 7 - 17
  • [2] Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
    Malick M. Gibani
    Elizabeth Jones
    Amber Barton
    Celina Jin
    Juliette Meek
    Susana Camara
    Ushma Galal
    Eva Heinz
    Yael Rosenberg-Hasson
    Gerlinde Obermoser
    Claire Jones
    Danielle Campbell
    Charlotte Black
    Helena Thomaides-Brears
    Christopher Darlow
    Christina Dold
    Laura Silva-Reyes
    Luke Blackwell
    Maria Lara-Tejero
    Xuyao Jiao
    Gabrielle Stack
    Christoph J. Blohmke
    Jennifer Hill
    Brian Angus
    Gordon Dougan
    Jorge Galán
    Andrew J. Pollard
    Nature Medicine, 2019, 25 : 1082 - 1088
  • [3] Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
    Gibani, Malick M.
    Jones, Elizabeth
    Barton, Amber
    Jin, Celina
    Meek, Juliette
    Camara, Susana
    Galal, Ushma
    Heinz, Eva
    Rosenberg-Hasson, Yael
    Obermoser, Gerlinde
    Jones, Claire
    Campbell, Danielle
    Black, Charlotte
    Thomaides-Brears, Helena
    Darlow, Christopher
    Dold, Christina
    Silva-Reyes, Laura
    Blackwell, Luke
    Lara-Tejero, Maria
    Jiao, Xuyao
    Stack, Gabrielle
    Blohmke, Christoph J.
    Hill, Jennifer
    Angus, Brian
    Dougan, Gordon
    Galan, Jorge
    Pollard, Andrew J.
    NATURE MEDICINE, 2019, 25 (07) : 1082 - +
  • [4] Human challenge trials in vaccine development
    Sekhar, Amrita
    Kang, Gagandeep
    SEMINARS IN IMMUNOLOGY, 2020, 50
  • [5] Acceptability of the gonorrhoea human challenge model to accelerate vaccine development in UK men
    Firth, C.
    Emary, K.
    Stuart, A.
    Browne, R.
    Williamson, M.
    Francis, E.
    Vanderslott, S.
    Hodgson, S. H.
    VACCINE, 2025, 54
  • [6] Generating the Evidence for Typhoid Vaccine Introduction: Considerations for Global Disease Burden Estimates and Vaccine Testing Through Human Challenge
    Meiring, James E.
    Giubilini, Alberto
    Savulescu, Julian
    Pitzer, Virginia E.
    Pollard, Andrew J.
    CLINICAL INFECTIOUS DISEASES, 2019, 69 : S402 - S407
  • [7] Considering human challenge trials for tuberculosis vaccine development
    Kleinwaks, Gavriel
    Schmit, Virginia
    Morrison, Josh
    VACCINE, 2022, 40 (02) : 173 - 174
  • [8] Innovative approach for the clinical development of a Chlamydia trachomatis vaccine through a human challenge model in women
    Cohen, Craig R.
    INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2025, 154
  • [9] Immune Modulation and the Development of Fowl Typhoid: A Model of Human Disease?
    Tang, Ying
    Jones, Michael
    Barrow, Paul A.
    Foster, Neil
    PATHOGENS, 2020, 9 (10): : 1 - 18
  • [10] Why the development of effective typhoid control measures requires the use of human challenge studies
    Jones, Claire
    Darton, Thomas C.
    Pollard, Andrew J.
    FRONTIERS IN MICROBIOLOGY, 2014, 5