NMR discovery and molecular-basis of small molecule inhibitors of STAT3

被引:0
|
作者
Namanja, Andrew T. [1 ]
Buettner, Ralf [1 ]
Jove, Richard [2 ]
Chen, Yuan [1 ]
机构
[1] City Hope Beckman Res Inst, Duarte, CA USA
[2] Vaccine & Gene Therapy Inst Florida, Port St Lucie, FL USA
关键词
D O I
10.1158/1538-7445.AM2014-1636
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1636
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors
    Brotherton-Pleiss, Christine
    Yue, Peibin
    Zhu, Yinsong
    Nakamura, Kayo
    Chen, Weiliang
    Fu, Wenzhen
    Kubota, Casie
    Chen, Jasmine
    Alonso-Valenteen, Felix
    Mikhael, Simoun
    Medina-Kauwe, Lali
    Tius, Marcus A.
    Lopez-Tapia, Francisco
    Turkson, James
    JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (01) : 695 - 710
  • [2] Small Molecule Inhibitors of STAT3 for Cancer Therapy
    Zhao, M.
    Jiang, B.
    Gao, F-H.
    CURRENT MEDICINAL CHEMISTRY, 2011, 18 (26) : 4012 - 4018
  • [3] Small molecule inhibitors of Stat3 signaling pathway
    Deng, Jinxia
    Grande, Fedora
    Neamati, Nouri
    CURRENT CANCER DRUG TARGETS, 2007, 7 (01) : 91 - 107
  • [4] Novel small molecule inhibitors of STAT3 in cancer
    Bhasin, Deepak
    Chettiar, Somsundaram
    Li, Chenglong
    Lin, Jiayuh
    Li, Pui Kai
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 241
  • [5] Design, synthesis, and studies of small molecule STAT3 inhibitors
    Bhasin, Deepak
    Cisek, Katryna
    Pandharkar, Trupti
    Regan, Nicholas
    Li, Chenglong
    Pandit, Bulbul
    Lin, Jiayuh
    Li, Pui-Kai
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (01) : 391 - 395
  • [6] Small Molecule Inhibitors of IL-6/STAT3 Signaling
    Ye Jiqing
    Yue Xiaohong
    Sun Liping
    PROGRESS IN CHEMISTRY, 2016, 28 (07) : 1099 - 1111
  • [7] Novel activators and small-molecule inhibitors of STAT3 in cancer
    Yang, Lehe
    Lin, Shichong
    Xu, Lingyuan
    Lin, Jiayuh
    Zhao, Chengguang
    Huang, Xiaoying
    CYTOKINE & GROWTH FACTOR REVIEWS, 2019, 49 : 10 - 22
  • [8] SMALL MOLECULE INHIBITORS OF STAT3: A COMPARATIVE ANALYSIS BY CELL BASED ASSAYS AND MOLECULAR DYNAMICS SIMULATIONS
    Brambilla, L.
    Laurini, E.
    Genini, D.
    Jovic, S.
    Pricl, S.
    Catapano, C. V.
    ANNALS OF ONCOLOGY, 2012, 23 : 36 - 36
  • [9] Small Molecule Inhibitors of Signal Transducer and Activator of Transcription 3 (Stat3) Protein
    Debnath, Bikash
    Xu, Shili
    Neamati, Nouri
    JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (15) : 6645 - 6668
  • [10] Discovery of Potential Natural STAT3 Inhibitors: An in silico Molecular Docking and Molecular Dynamics Study
    Gul, Sameena
    Muhammad, Shabbir
    Irfan, Muhammad
    Belali, Tareg M.
    Chaudhry, Aijaz Rasool
    Khan, Muhammad
    JOURNAL OF COMPUTATIONAL BIOPHYSICS AND CHEMISTRY, 2024, 23 (02): : 189 - 205