Four new fluorenone alkaloids and one new dihydroazafluoranthene alkaloid from Caulophyllum robustum Maxim

被引：24
|
作者：
Wang, Xiao-Ling [1 ]
Liu, Bing-Rui [1 ,3 ]
Chen, Chien-Kuang [2 ]
Wang, Jun-Ru [3 ]
Lee, Shoei-Sheng [2 ]
机构：
[1] Baoji Univ Arts & Sci, Key Lab Phytochem Shaanxi Prov, Baoji 721013, Peoples R China
[2] Natl Taiwan Univ, Coll Med, Sch Pharm, Taipei 100, Taiwan
[3] NW Agr & Forest Univ, Coll Sci, Yangling 712100, Peoples R China
来源：
FITOTERAPIA | 2011年 / 82卷 / 06期
关键词：
Caulophyllum robustum; Fluorenone alkaloid; Dihydroazafluoranthene alkaloid; DPPH radical scavenging effects; SINOMENIUM-ACUTUM;
D O I：
10.1016/j.fitote.2011.04.010
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Four new fluorenone alkaloids, caulophylline A-D (1-4), and one new dihydroazafluoranthene alkaloid, caulophylline E (5) were isolated from the roots of Caulophyllum robustum Maxim. Their structures were elucidated by spectroscopic analysis. Among the isolated alkaloids, Caulophylline E showed good scavenging effects against DPPH radical with IC(50) of 39 mu M. (C) 2011 Published by Elsevier B.V.
引用
收藏
页码：793 / 797
页数：5
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