Simulation of wagon wheel optical fiber biosensor for quick and easy detection of cancer cells

In this study, a portable micro-structured three-channel plasmonic biosensor was simulated using the finite element method. The main feature of the proposed biosensor was the presence of three resonant wavelengths for a given biomaterial. This feature reduces measurement error as compared with the single-read biosensor. A high refractive index resolution in the order of 10(-6) and sensitivity in the order of 10(5) was calculated for the proposed biosensor. Considering refractive indices of several samples containing cancer cells, such as Jurkat, HeLa, PC12, and MDA-MB-231, which are respectively indicator cells for leukemia, cervical cancer, Adrenal medulla cells, and breast cancer, the three resonant wavelengths were determined for samples. The sensitivity of this biosensor as a function of its length was investigated for a given cancer cell sample.