SURNATANTS FROM SYSTEMIC SCLEROSIS PBMCS CO-CULTURED WITH AUTOLOGOUS FIBROBLASTS DISPLAY HIGH LEVELS OF PRO-FIBROTIC CYTOKINES

被引:0
|
作者
D'Aiuto, E. [1 ]
Vettori, S. [1 ]
Ranaldi, D. [1 ]
Pasquale, G. [1 ]
Barra, G. [1 ]
De Palma, R. [1 ]
Valentini, G. [1 ]
机构
[1] Univ Naples 2, Clin & Expt Med Dept, Naples, Italy
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:S109 / S109
页数:1
相关论文
共 29 条
  • [1] Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity
    Cutolo, Maurizio
    Gotelli, Emanuele
    Montagna, Paola
    Tardito, Samuele
    Paolino, Sabrina
    Pizzorni, Carmen
    Sulli, Alberto
    Smith, Vanessa
    Soldano, Stefano
    ARTHRITIS RESEARCH & THERAPY, 2021, 23 (01)
  • [2] Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity
    Maurizio Cutolo
    Emanuele Gotelli
    Paola Montagna
    Samuele Tardito
    Sabrina Paolino
    Carmen Pizzorni
    Alberto Sulli
    Vanessa Smith
    Stefano Soldano
    Arthritis Research & Therapy, 23
  • [3] Functional changes in scleroderma fibroblasts co-cultured with autologous peripheral blood mononuclear cells (PBMCS)
    Vettori, S.
    De Palma, R.
    Malanga, D.
    D'Aiuto, E.
    Zekusic, M.
    Abbate, G.
    Valentini, G.
    ANNALS OF THE RHEUMATIC DISEASES, 2007, 66 : A66 - A66
  • [4] Correction: Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity
    Maurizio Cutolo
    Emanuele Gotelli
    Paola Montagna
    Samuele Tardito
    Sabrina Paolino
    Carmen Pizzorni
    Alberto Sulli
    Vanessa Smith
    Stefano Soldano
    Arthritis Research & Therapy, 25
  • [5] The Role of Pro-fibrotic Myofibroblasts in Systemic Sclerosis: From Origin to Therapeutic Targeting
    Romano, Eloisa
    Rosa, Irene
    Fioretto, Bianca Saveria
    Matucci-Cerinic, Marco
    Manetti, Mirko
    CURRENT MOLECULAR MEDICINE, 2022, 22 (03) : 209 - 239
  • [6] DIFFERENTIATION RESPONSES OF BONE MARROW DERIVED MESENCHYMAL STEM CELLS FROM SYSTEMIC SCLEROSIS PATIENTS TO PRO-FIBROTIC CYTOKINES
    Hegner, B.
    Catar, R.
    Kusch, A.
    Essin, K.
    Naether, M.
    Gollasch, M.
    Riemekasten, G.
    Dragun, D.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2010, 28 (02) : S148 - S148
  • [7] NINTEDANIB (TYROSINE KINASE INHIBITOR) DOWNREGULATES THE TRANSITION OF CULTURED SYSTEMIC SCLEROSIS FIBROCYTES INTO MYOFIBROBLASTS AND THEIR PRO-FIBROTIC ACTIVITY
    Soldano, S.
    Montagna, P.
    Gotelli, E.
    Tardito, S.
    Paolino, S.
    Corallo, C.
    Pizzorni, C.
    Sulli, A.
    Schenone, C.
    Pacini, G.
    Smith, V.
    Cutolo, M.
    ANNALS OF THE RHEUMATIC DISEASES, 2021, 80 : 392 - 392
  • [8] PERIPHERAL BLOOD MONONUCLEAR CELLS CO-CULTURED WITH AUTOLOGOUS SKIN FIBROBLASTS UP-REGULATE IL-17A AND PLAY ANTI-FIBROTIC EFFECTS IN SYSTEMIC SCLEROSIS
    Vettori, S.
    Pasquale, G.
    Ludici, M.
    Cuomo, G.
    Russo, B.
    Barra, G.
    De Palma, R.
    Valentini, G.
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 : 576 - 576
  • [9] Peripheral T lymphocytes from patients with early systemic sclerosis co-cultured with autologous fibroblasts undergo an oligoclonal expansion similar to that occurring in the skin
    De Palma, R
    Del Galdo, F
    Lupoli, S
    Altucci, P
    Abbate, G
    Valentini, G
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2006, 144 (01): : 169 - 176
  • [10] IL-17A UP-REGULATION IN PERIPHERAL BLOOD MONONUCLEAR CELLS CO-CULTURED WITH AUTOLOGOUS SKIN FIBROBLASTS IS ASSOCIATED WITH DOWN-REGULATION OF PRO-FIBROTIC MEDIATORS AND INCREASED FIBROBLAST APOPTOSIS
    Vettori, S.
    Barra, G.
    Pasquale, G.
    Pellecchia, L.
    Vicedomini, L.
    De Palma, R.
    Valentini, G.
    ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 621 - 621