The Removal of Protein-Bound Solutes by Dialysis

被引:10
|
作者
Meyer, Timothy W. [1 ,2 ]
机构
[1] VA Palo Alto HCS, Dept Med Nephrol, Palo Alto, CA USA
[2] Stanford Univ, Dept Med Nephrol, Palo Alto, CA 94304 USA
关键词
INDOXYL SULFATE; HEMODIALYSIS-PATIENTS; PERITONEAL-DIALYSIS; MASS-TRANSFER; P-CRESOL; ACCUMULATION; CLEARANCE; SORBENT; FAILURE; TOXINS;
D O I
10.1053/j.jrn.2011.10.011
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Protein-bound solutes that accumulate in plasma when the kidneys fail are poorly cleared by conventional dialysis. Means have been developed to reduce the levels of such solutes, either by modifying the dialysis procedure to increase their clearance or by limiting their production. A trial testing whether reducing bound solute levels clinically benefits dialysis patients is required to determine whether these measures should be adopted in routine clinical practice. Published by the National Kidney Foundation, Inc.
引用
收藏
页码:203 / 206
页数:4
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