A cascade reaction of pyrrole-2-carbaldehyde substituted Morita-Baylis-Hillman adducts in the presence of tetrabutylammonium hydroxide or acetate to construct aza-heterocycles

被引：11
|
作者：
Huang, Long [1 ,2 ]
Shi, Min [1 ,2 ,3 ]
机构：
[1] E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China
[2] E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China
[3] Chinese Acad Sci, State Key Lab Organometall Chem, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 37期
基金：
中国国家自然科学基金;
关键词：
ONE-POT; CATALYZED REARRANGEMENT; ALLYLIC ALKYLATION; ISOMERIZATION; FACILE; ALDEHYDES; MILD;
D O I：
10.1039/c2cc31358h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The phase-transfer catalyst promoted intramolecular transformation of pyrrole-2-carbaldehyde substituted Morita-Baylis-Hillman adducts has been disclosed, providing an efficient way to construct pyrrolo[1,2-a]azepin-7(6H)-one skeletons in moderate to good yields (up to 92%) under mild conditions.
引用
收藏
页码：4501 / 4503
页数：3
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