Prospective cohort study of risk factors for choroidal detachment after trabeculectomy

Purpose To investigate risk factors for choroidal detachment after trabeculectomy. Methods We prospectively evaluated 97 patients with open-angle glaucoma who underwent primary trabeculectomy to investigate risk factors for choroidal detachment after trabeculectomy. The primary outcome measure was risk factors for the occurrence and severity of choroidal detachment after trabeculectomy. Choroidal detachment severity was quantified as the number of fundus quadrants with choroidal detachment. Results Sixteen patients (16.5%) had choroidal detachment. Mean period between surgery and occurrence of choroidal detachment was 7.9 +/- 5.7 days. Mean intraocular pressure (IOP) on the first day of choroidal detachment was 6.1 +/- 3.0 mm Hg. Multivariable analyses revealed that the exfoliation glaucoma, greater Delta IOP between preoperative and lowest postoperative IOPs, and thicker cornea were associated with choroidal detachment (P = 0.022, P = 0.002, and P = 0.013, respectively). These factors were also associated with the severity of choroidal detachment (exfoliation glaucoma; P = 0.013, greater Delta IOP; P < 0.001, and thicker cornea; P = 0.006). Conclusions Exfoliation glaucoma, more IOP reduction, and thicker cornea are associated with the occurrence and severity of choroidal detachment after trabeculectomy.