On the mechanism of long-range electron transfer through DNA

被引：0
|
作者：
Giese, B
Wessely, S
Spormann, M
Lindemann, U
Meggers, E
Michel-Beyerle, ME
机构：
[1] Univ Basel, Dept Chem, CH-4056 Basel, Switzerland
[2] Tech Univ Munich, Inst Phys & Theoret Chem, D-85748 Garching, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1999年 / 38卷 / 07期
关键词：
bioorganic chemistry; DNA oxidation; electron transfer; radicals;
D O I：
10.1002/(SICI)1521-3773(19990401)38:7<996::AID-ANIE996>3.0.CO;2-4
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Hopping between bases of similar redox potentials is the mechanism by which charge transport occurs through DNA. This was shown by rate measurements performed with double strands 1-3. This mechanism explains why hole transfer displays a strong sequence dependence, and postulates that electron transfer in unperturbed DNA should not be dependent on the sequence.
引用
收藏
页码：996 / 998
页数：3
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