High resolution mass spectrometry for single cell analysis

被引：5
|
作者：
Nisar, Muhammad Shemyal [1 ,2 ]
Zhao, Xiangwei [1 ,2 ]
机构：
[1] Southeast Univ, Sch Biol Sci & Med Engn, State Key Lab Bioelect, Nanjing 210096, Peoples R China
[2] Southeast Univ Shenzhen Res Inst, Shenzhen 518000, Peoples R China
来源：
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY | 2020年 / 450卷
基金：
中国国家自然科学基金;
关键词：
Single cell; Mass spectrometry; MALDI; Nanophotonics; Laser ablation; ASSISTED-LASER-DESORPTION/IONIZATION; FAST-ATOM-BOMBARDMENT; ABLATION ELECTROSPRAY-IONIZATION; HIGH-SPATIAL-RESOLUTION; ATMOSPHERIC-PRESSURE; LATERAL RESOLUTION; SIMS ANALYSIS; ION-SOURCE; DESORPTION; FORCE;
D O I：
10.1016/j.ijms.2020.116302
中图分类号：
O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号：
070203 ; 070304 ; 081704 ; 1406 ;
摘要：
Mass spectrometry is an important analytical tool that has found pervasive use in numerous fields. This review tries to look at the recent advances in high resolution mass spectrometry for single cell analysis. This manuscript is specifically focused at the developments, progresses and bottle necks in the resolution of the instruments developed for of mass spectrometry. These advances have been able to foment further challenges which require further research. This paper attempts to highlight these challenges and alludes to possible solutions for these challenges. (C) 2029 Elsevier B.V. All rights reserved.
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页数：10
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