Phase II study of the PARP inhibitor talazoparib (BMN-673) in advanced cancer patients with somatic alterations in BRCA1/2, mutations/deletions in PTEN or PTEN loss, a homologous recombination defect, mutations/deletions in other BRCA pathway genes and germline mutation S in BRCA1/2 (not breast or ovarian cancer).

被引：3
|
作者：
Piha-Paul, Sarina Anne
Goldstein, Jennifer Brooke
Hess, Kenneth R.
Fu, Siqing
Hong, David S.
Janku, Filip
Karp, Daniel D.
Naing, Aung
Subbiah, Vivek
Tsimberidou, Apostolia Maria
Wheler, Jennifer J.
Zinner, Ralph
Mills, Gordon B.
Meric-Bernstam, Funda
机构：
[1] Univ Texas MD Anderson Canc Ctr, Dept Invest Canc Therapeut, Phase Program 1, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[3] Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77030 USA
[4] Univ Texas MD Anderson Canc Ctr, Dept Syst Biol, Houston, TX 77030 USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2015年 / 33卷 / 15期
关键词：
D O I：
10.1200/jco.2015.33.15_suppl.tps2617
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
TPS2617
引用
收藏
页数：1
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