This paper was to investigate the relationship between future time perspective and depression of college students by using the general future time perspective questionnaire and SDS. Results were as follows: (1) There was no significant difference between male and female college students. There was a significant difference between arts students and science students, science students got higher score in behavior commitment and purpose awareness than arts students. (2) Behavior commitment, future efficiency and future image in future time perspective were positive related to physical disorder, psychomotor activity disorder, mental disorder of depression; purpose awareness was positive related to psychotropic-affective symptoms, physical disorder, psychomotor activity disorder and mental disorder of depression. (3) There was a significant difference between the students who got high score and the ones who got low score at future time perspective in physical disorder, psychomotor activity disorder, mental disorder of depression. (4) Purpose awareness and far-reach goal orientation can significantly predict psychotropic-affective symptoms of depression, purpose awareness can significantly predict physical disorder and psychomotor activity disorder of depression, purpose awareness and future image can significantly predict mental disorder of depression.