Vitamin D Deficiency and Early Implant Failure: Outcomes from a Pre-surgical Supplementation Program on Vitamin D Levels and Antioxidant Scores

被引:2
|
作者
Paz, Ana [1 ]
Stanley, Miguel [1 ]
Mangano, Francesco Guido [2 ]
Miron, Richard J. [3 ]
机构
[1] White Clin, Private Practice, Lisbon, Portugal
[2] Univ Varese, Dent Sch, Dept Med & Surg, Varese, Italy
[3] Univ Bern, Sch Dent Med, Dept Periodontol, Bern, Switzerland
关键词
DentaMedica; early implant failure; implant integration; osseointegration; vitamin D deficiency; BONE; OSSEOINTEGRATION; PREVENTION;
D O I
10.3290/j.ohpd.b2082063
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Purpose: Accumulating evidence has shown that vitamin D deficiency has been linked with an up to 300% increase in early implant failure. The aim of this study was to investigate a comprehensive pre-surgical dental support program (DentaMedica) on its ability to increase vitamin D and antioxidant levels prior to implant surgery. Materials and Methods: Twenty patients were enrolled in this study. To quantify vitamin D levels, two in-office vitamin D finger-prick tests (10-15 min in length) were compared to levels obtained from a standard laboratory blood test. An antioxidant testing device was also utilised to investigate the impact of this pre-surgical supplementation program on antioxidant scores 0 and 6 weeks post supplementation. Results: It was first found that 65% of the population had an initial vitamin D deficiency (below 30 ug/ml). After supplementation, vitamin D levels increased from an average of 24.76 ng/ml to 50.11 ng/ml (ranging from 38 to 85.50 ng/ml). No statsitcally significant differences were observed between any of the 3 testing devices (2 in-office finger-prick tests and a standard blood sample). Initial antioxidant levels registered on the biophotonic unit averaged an antioxidant score of 27250 +/- 10992.22. Following supplementation, an increase of 54% from baseline values (41950 +/- 9276.31) was reported. Conclusion: The results from this study show convincingly that the majority of the tested population was vitamin D deficient. It was further found that both in-office finger-prick devices demonstrated results comparable to standard lab scores (usually within an average 2-3 ng/ml). Following supplementation, all patients reached sufficient levels following this 4-6 week pre-surgical supplementation program specific to implant dentistry.
引用
收藏
页码:495 / 501
页数:7
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