Anemia Combined Significantly Increased High-Sensitivity C Reactive Protein and Lung Lesions Lead to the Diagnosis of Granulomatosis with Polyangiitis Proven by Lung Biopsy and Anti-neutrophil Cytoplasmic Antibody Test

被引：3

作者：

Ge, Yan L. ^{[1
]}

Liu, Cong H. ^{[2
]}

Wang, Meng H. ^{[3
]}

Zhang, Jia B. ^{[1
]}

Chen, Hao ^{[4
]}

Zhu, Xiao Y. ^{[1
]}

Li, Zhen Z. ^{[1
]}

Li, Hong L. ^{[1
]}

Cui, Zi Y. ^{[1
]}

Li, Li Q. ^{[1
]}

Fu, Ai S. ^{[1
]}

Wang, Hong Y. ^{[1
]}

机构：

[1] North China Univ Sci & Technol, Affiliated Hosp, Dept Resp Med, Jianshe Rd 73, Tangshan 063000, Hebei, Peoples R China

[2] North China Univ Sci & Technol, Affiliated Hosp, Dept Endocrinol Med, Tangshan, Hebei, Peoples R China

[3] North China Univ Sci & Technol, Affiliated Hosp, Dept Hosp Informat Management, Tangshan, Hebei, Peoples R China

[4] North China Univ Sci & Technol, Affiliated Hosp, Dept Cardiovasc Med, Tangshan, Hebei, Peoples R China

来源：

CLINICAL LABORATORY | 2019年 / 65卷 / 1-2期

关键词：

granulomatosis with polyangiitis; anti-neutrophil cytoplasmic antibody; anemia; hs-CRP;

D O I：

10.7754/Clin.Lab.2018.180733

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Background: To report an atypical case misdiagnosed as lung abscess over the past 2 months, but persistent anemia combined with significantly increased hs-CRP and lung lesions indicated systemic lesion, which led to the diagnosis of granulomatosis with polyangiitis proven by lung biopsy and anti-neutrophil cytoplasmic antibody test (ANCA). Methods: The complete blood count, hs-CRP, and anti-neutrophil cytoplasmic antibody (ANCA) test were performed. The pathology consultation for the lung biopsy was arranged. Results: Hemoglobin was 8.5 g/L, hs-CRP was > 200 mg/L, c-ANCA directed against anti-proteinase 3 (PR3) was positive, pathology consultation reported granulomatous inflammation. Conclusions: When patients have multiple organ dysfunction combined with anemia and significantly increased hs-CRP, physicians should pay attention to systemic vasculitis.

引用

页码：187 / 189

页数：3

共 1 条

[1] Myeloperoxidase Anti-Neutrophil Cytoplasmic Antibody-Positive Interstitial Pneumonia Associated with Granulomatosis with Polyangiitis Diagnosed by Surgical Lung Biopsy
Chino, Haruka
Hagiwara, Eri
Kitamura, Hideya
Baba, Tomohisa
Yamakawa, Hideaki
Takemura, Tamiko
Ogura, Takashi
RESPIRATION, 2016, 92 (05) : 348 - 355

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