Glucose Molecularly Imprinted Electrochemical Sensor Based on Chitosan and Nickel Oxide Electrode

In this work, A molecularly imprinted polymers (MIPs) electrochemical sensor based on chitosan (CS) and nickel electrode was constructed, finally used in glucose measurement. The MIPs sensor was prepared through electrodepositing glucose-CS composited film on the electrochemical treated nickel then removing glucose from the film via water elution. The morphology and electrochemical properties of the sensor were characterized via scanning electron microscope (SEM), cyclic voltammetry (CV), respectively. Amperometric responses of the CS (MIP)-NiO electrode toward glucose was well-proportional to the concentration of the range from 10 mu M to 200 mu M. The developed sensor obtained the specific recognition to glucose against coexisting interferences such as oxalic acid, uric acid and ascorbic acid.