FeCl3-promoted alkylation of indoles by enamides

被引：30
|
作者：
Niu, Tianmin [1 ]
Huang, Lehao [1 ]
Wu, Tianxing [1 ]
Zhang, Yuhong [1 ]
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2011年 / 9卷 / 01期
关键词：
FRIEDEL-CRAFTS ALKYLATION; CROSS-COUPLING REACTIONS; SPONGE SPONGOSORITES SP; ARYL GRIGNARD-REAGENTS; CATALYZED N-ARYLATION; CHIRAL BRONSTED ACID; C-H BOND; VIBRIO-PARAHAEMOLYTICUS; UNACTIVATED ALKENES; IRON CATALYSIS;
D O I：
10.1039/c0ob00709a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient iron-promoted alkylation of indoles with enamides has been accomplished under mild reaction conditions. The reaction proceeded with remarkable regioselectivity leading exclusively to substitution by indoles at alpha-position of enamides.
引用
收藏
页码：273 / 277
页数：5
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