Synthesis of specifically labelled ganglioside [1c-13C]-GM3

被引：0

作者：

Tietze, LF ^{[1
]}

Gretzke, D ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ Chem, D-37077 Gottingen, Germany

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 1998卷 / 09期

关键词：

gangliosides; carbohydrates; sialic acid; tumor therapy; glycosides;

D O I：

10.1002/(SICI)1099-0690(199809)1998:9<1895::AID-EJOC1895>3.0.CO;2-S

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Glycosidation of the lactose derivative 4 with [1-C-13]-sialyl xanthate 3, prepared from enzymatically obtained [1-C-13]-sialic acid gave the trisaccharide 5 which was transformed into [1c-C-13]-GM(3) ([1c-C-13]-1).

引用

页码：1895 / 1899

页数：5

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