Clinical and demographic characteristics of cervical cancer patients presenting at Parirenyatwa Hospital, Zimbabwe

被引:1
|
作者
Kuguyo, Oppah [1 ,4 ]
Tsikai, Nomsa [2 ]
Muradzikwa, Senelisiwe Chipo [3 ]
Mhandire, Kudakwashe [4 ]
Nhachi, Charles [1 ]
Magwali, Thulani [5 ]
Madziyire, Mugove G. [5 ]
Matimba, Alice [6 ]
Dandara, Collet [4 ,7 ]
机构
[1] Univ Zimbabwe, Coll Hlth Sci, Dept Clin Pharmacol, Harare, Zimbabwe
[2] Univ Zimbabwe, Coll Hlth Sci, Dept Oncol, Harare, Zimbabwe
[3] Univ Witwatersrand, Dept Stat, Johannesburg, South Africa
[4] Univ Cape Town, Fac Hlth Sci, Div Human Genet, Dept Pathol, 1 Anzio Rd, Cape Town, South Africa
[5] Univ Zimbabwe, Dept Obstet & Gynaecol, Coll Hlth Sci, Harare, Zimbabwe
[6] Wellcome Genome Campus, Adv Courses & Sci Conferences, Hinxton, England
[7] Univ Cape Town, Inst Infect Dis & Mol Med, Fac Hlth Sci, Cape Town, South Africa
来源
关键词
Clinicopathological profile; black African; cervical cancer; chemotherapy; Zimbabwe; SCHISTOSOMA-HAEMATOBIUM; CLINICOPATHOLOGICAL CORRELATION; PERIPHERAL NEUROPATHY; HUMAN-PAPILLOMAVIRUS; UTERINE CERVIX; RISK-FACTORS; CHEMOTHERAPY; CARCINOMA; HIV; CHEMORADIATION;
D O I
10.29063/ajrh2021/v25i6.11
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Cervical cancer is the leading cause of cancer deaths in women in Africa, predominately due to late diagnosis. This study aims to identify risk factors, potential prognostic indicators, and optimal treatment modalities for Zimbabwean cervical cancer patients. Medical records for 1063 cervical cancer patients were reviewed for sociodemographic, clinical, treatment, and response data. All data were analysed using SPSS version 25. More than half of the cohort was pre-menopausal (63%) with low (2%) history of cervical cancer screening. Schistosoma ova were observed in 2.4% of the tumour specimens. More than 50% were diagnosed at stage 3 and later, with a high frequency of comorbidities (similar to 68%). This study highlights a need for improving screening education and uptake in Zimbabwe. Moreover, the current data provides a dataset for understanding cervical cancer pathogenesis and treatment responses in an African cohort.
引用
收藏
页码:99 / 109
页数:11
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