Microwave Assistant Synthesis of Gold Nanoparticles and Their Application in Protein Determination

Herein, we report a novel microwave(MW) assistant method for gold nanoparticle synthesis. The formation of gold nanoparticles occurs rapidly in single step, carried out by directly heating the reaction mixture of HAuCl(4) with sodium citrate in the MW reactor. The particle size and size distribution can be controlled by subtle variation of the ratio of HAuCl(4) to sodium citrate in the mixture. After functionalisation, the application of the as-prepared gold nanoparticles for protein determination was also demonstrated.