Nanocellulose conjugated with retinoic acid: its capability to adsorb aflatoxin B1

被引：12

作者：

Jebali, Ali ^{[1
,2
]}

Ardakani, Seyed Ali Yasini ^{[2
]}

Sedighi, Najme ^{[2
]}

Hekmatimoghaddam, Seyedhossein ^{[3
]}

机构：

[1] Shahid Sadoughi Univ Med Sci, Dept Med Genet, Yazd, Iran

[2] Islamic Azad Univ, Coll Agr, Dept Food Sci, Yazd 8916733754, Iran

[3] Shahid Sadoughi Univ Med Sci, Sch Paramed, Dept Lab Sci, Yazd, Iran

来源：

CELLULOSE | 2015年 / 22卷 / 01期

关键词：

Nanocellulose; Retinoic acid; Adsorption; Aflatoxin B1; HEPATOCELLULAR-CARCINOMA; IN-VITRO; AFLATOXICOSIS; LYSOZYME; EXPOSURE; BINDING; CLAY; VIVO; B-1;

D O I：

10.1007/s10570-014-0475-0

中图分类号：

TB3 [工程材料学]; TS [轻工业、手工业、生活服务业];

学科分类号：

0805 ; 080502 ; 0822 ;

摘要：

The main aim of this study was to evaluate the adsorption of aflatoxin B1 by nanocellulose conjugated with retinoic acid (NCRA). First, aflatoxin B1 and NCRA were modeled in the Hyperchem software, and then the adsorption of aflatoxin B1 was simulated by the molecular dynamics technique. Second, nanocellulose was synthesized and conjugated with retinoic acid by cross-linker. Third, the adsorption of aflatoxin B1 and NCRA and its release were evaluated at different conditions. Fourth, its adsorption was evaluated in different foodstuffs. Sixth, its toxicity was evaluated on mouse esophageal cells (MECs). Computer-based simulation showed the adsorption of aflatoxin B1 by NCRA. This study showed that the adsorption and release were less affected by temperature and incubation time but highly affected by pH and concentration. Moreover, it was found that NCRA could adsorb aflatoxin B1 in different foodstuffs. Importantly, NCRA had no remarkable toxicity on the MECs.

引用

页码：363 / 372

页数：10

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