WP1130, a small molecular weight compound, inhibits JAK2-STAT3 signaling through a unique degradation mechansim

被引：0
|
作者：
Kapuria, Vaibhav [1 ]
Bartholomeusz, Geoffrey [1 ]
Priebe, Waldemar [1 ]
Kong, Ling Y. [1 ]
Talpaz, Moshe [1 ]
Donato, Nicholas [1 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
来源：
CANCER RESEARCH | 2006年 / 66卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3012
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Inhibition of Cytokine Signaling through Activation of Jak2 Ubiquitination by WP1130
    Kapuria, Vaibhav
    Peterson, Luke F.
    Bommann, William
    Talpaz, Moshe
    Donato, Nicholas J.
    BLOOD, 2009, 114 (22) : 1136 - 1136
  • [2] Magnesium Lithospermate B Inhibits Colorectal Cancer Cell Progression Through JAK2-STAT3 Signaling
    Huo, Dan
    Zhang, Jinpeng
    Ma, Tengfei
    Liu, Yemao
    Zhang, Jianqing
    Dong, Bizhen
    Lu, Yanjun
    Wu, Anding
    Jin, Zhaoxia
    Li, Yuping
    DNA AND CELL BIOLOGY, 2024, 43 (12) : 619 - 629
  • [3] Anlotinib inhibits the progress of colorectal cancer cells by antagonizing glycolysis & JAK2-STAT3 signaling
    Jia, Zhenxian
    Zhang, Zhi
    Li, Ze
    Li, Ang
    Xie, Yuning
    Wu, Hongjiao
    Yang, Zhenbang
    Zhang, Hongmei
    Zhang, Xuemei
    CANCER RESEARCH, 2020, 80 (16)
  • [4] Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway
    Dong, Yanmin
    Lu, Binbin
    Zhang, Xiaoli
    Zhang, Jing
    Lai, Li
    Li, Dali
    Wu, Yuanyuan
    Song, Yajuan
    Luo, Jian
    Pang, Xiufeng
    Yi, Zhengfang
    Liu, Mingyao
    CARCINOGENESIS, 2010, 31 (12) : 2097 - 2104
  • [5] Influence of Compound Shougong Powder on JAK2-STAT3 Signaling Pathway in Mice with Lewis Lung Cancer
    Shen Di
    Li Chong-hui
    JOURNAL OF INTERNATIONAL TRANSLATIONAL MEDICINE, 2014, 2 (04): : 476 - 481
  • [6] Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling
    Wang, Jiajia
    Wang, Jiaying
    Hong, Wenxiang
    Zhang, Lulu
    Song, Liqian
    Shi, Qi
    Shao, Yanfei
    Hao, Guifeng
    Fang, Chunyan
    Qiu, Yueping
    Yang, Lijun
    Yang, Zhaoxu
    Wang, Jincheng
    Cao, Ji
    Yang, Bo
    He, Qiaojun
    Weng, Qinjie
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [7] Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling
    Jiajia Wang
    Jiaying Wang
    Wenxiang Hong
    Lulu Zhang
    Liqian Song
    Qi Shi
    Yanfei Shao
    Guifeng Hao
    Chunyan Fang
    Yueping Qiu
    Lijun Yang
    Zhaoxu Yang
    Jincheng Wang
    Ji Cao
    Bo Yang
    Qiaojun He
    Qinjie Weng
    Nature Communications, 12
  • [8] Schizandrin A Inhibits Microglia-Mediated Neuroninflammation through Inhibiting TRAF6-NF-κB and Jak2-Stat3 Signaling Pathways
    Song, Fangjiao
    Zeng, Kewu
    Liao, Lixi
    Yu, Qian
    Tu, Pengfei
    Wang, Xuemei
    PLOS ONE, 2016, 11 (02):
  • [9] miR-375 inhibits Helicobacter pylori-induced gastric carcinogenesis by blocking JAK2-STAT3 signaling
    Miao, Lin
    Liu, Kunmei
    Xie, Meijuan
    Xing, Yingying
    Xi, Tao
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2014, 63 (07) : 699 - 711
  • [10] Midazolam Inhibits the Apoptosis of Astrocytes Induced by Oxygen Glucose Deprivation via Targeting JAK2-STAT3 Signaling Pathway
    Liu, Li
    You, Qi
    Tu, Yingfeng
    Li, Quanyi
    Zheng, Lihong
    Li, Xuan
    Gu, Jing
    Wang, Guonian
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2015, 35 (01) : 126 - 136
12345