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Successful re-transplantation in patient with recurrent parvovirus B19 pure red cell aplasia
被引:2
|作者:
Inamdar, Neeraj
[1
]
Nada, Ritambhra
[2
]
Minz, Ranjana
[3
]
Kenwar, Deepesh Benjamin
[4
]
Singh, Sarabpreet
[4
]
Sharma, Ashish
[4
]
Kumar, Vivek
[1
]
Rathi, Manish
[1
]
Kohli, Harbir S.
[1
]
Ramachandran, Raja
[1
]
机构:
[1] Post Grad Inst Med Educ & Res, Dept Nephrol, Chandigarh, India
[2] Post Grad Inst Med Educ & Res, Dept Histopathol, Chandigarh, India
[3] Post Grad Inst Med Educ & Res, Dept Immunopathol, Chandigarh, India
[4] Post Grad Inst Med Educ & Res, Dept Transplant Surg, Chandigarh, India
关键词:
collapsing glomerulopathy;
parvovirus B19;
pure red cell aplasia;
re-transplantation;
D O I:
10.1111/tid.13164
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
Impaired cell-mediated, as well as antibody-mediated immunity predisposes a renal transplant recipient to a wide variety of atypical infection. With an increasing number of re-transplant, the balance between immunosuppression and the risk of recurrent disease poses a clinical and therapeutic challenge. Here, we report a successful re-transplantation in a case of parvovirus B19 infection leading to anaemia and collapsing glomerulopathy in the allograft managed with intravenous immunoglobulin (IVIG) and reduction of immunosuppression. This case emphasizes re-consideration to renal transplant after clearance of the virus in a previous renal allograft lost to PVB19 infection.
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