Modification of the fatty acid composition in lipids of the yeast Candida maltosa and its effect on the physiological and biochemical features of the cells

Cerulenin, which is known to inhibit the de novo synthesis of fatty acid chains, exerted no noticeable effect on the growth rate of Candida maltosa yeast cultivated with hexadecane as the sole carbon source, but caused an increase in the level of C-16 acids from 10 to 62% of the total fatty acids. Modification of the fatty-acid composition of lipids led to greater heat release by cells, changed the kinetic parameters of amino-acid transport, and influenced the rate of protein synthesis at low and high temperatures.