Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum

被引：61

作者：

Song, YS

Kim, SH

Sa, JH

Jin, C

Lim, CJ

Park, EH ^{[1
]}

机构：

[1] Sookmyung Womens Univ, Coll Pharm, Seoul 140742, South Korea

[2] Korea Inst Sci & Technol, Bioanal & Biotransformat Res Ctr, Seoul 130650, South Korea

[3] Kangwon Res Inst Hlth & Environm, Dept Food & Drug Anal, Chunchon 200093, South Korea

[4] Kangweon Natl Univ, Dept Chem, Div Life Sci, Chunchon 200701, South Korea

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2004年 / 90卷 / 01期

关键词：

ganoderma lucidum; anti-angiogenic activity; nitric oxide; folk medicine;

D O I：

10.1016/j.jep.2003.09.006

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Fresh fruit bodies of Ganoderma lucidum were extracted with 70%. ethanol at room temperature. The extract (GL) showed significant anti-angiogenic activity, which was detected using a chick embryo chorioallantoic membrane assay. GL significantly inhibited LPS-induced NO production in RAW 264.7 macrophages. These results support the anti-tumor effect of Ganoderma lucidum. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

引用

页码：17 / 20

页数：4

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