Mammary pseudoangiomatous stromal hyperplasia presenting as an axillary mass

被引:19
|
作者
Lee, JS
Oh, HS
Min, KW
机构
[1] Chonnam Natl Univ, Hwasun Hosp, Dept Pathol, Sch Med, Jeollanamdo 519809, South Korea
[2] Seonam Univ, Coll Med, Dept Pathol, Namwon, South Korea
[3] Deaconess Hosp, Dept Pathol, Oklahoma City, OK USA
来源
BREAST | 2005年 / 14卷 / 01期
关键词
breast; pseudoangiomatous stromal hyperplasia; axilla; hormone;
D O I
10.1016/j.breast.2004.09.013
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Pseudoangiomatous stromal hyperplasia (PASH) of the breast is characterized by interanastomosing slit-like spaces tined with spindle-shaped cells in an abundant fibrous stroma. PASH is a relatively common incidental finding in the breast tissue removed for other reasons and rarely presents as a localized mass. The etiology of PASH is unknown, but hormonal factors are thought to be involved. Accessory breast tissue is subject to all pathologic changes found in the normal breast. We report a case of PASH that presented as a palpable axillary mass in a 43-year-old woman. To our knowledge, PASH has not previously been reported in the axillary accessory breast tissue. The spindle stromal cells in our patient showed immunophenotypic characteristics of myofibroblastic differentiation. Immunoreactivity for progesterone receptor was noted in the spindle cells. These findings support the hypothesis that endogenous hormones are involved in the development of PASH. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:61 / 64
页数:4
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