Aetiology and pathogenesis of HNF1A-MODY using human islets deficient of HNF1A and a new heterozygous mouse model (Hnf1aΔe4-10) of the human disease

被引：0
|
作者：
Acosta Montalvo, A. [1 ,2 ]
Saponaro, C. [1 ]
Thevenet, J. [1 ]
Chiral, M. [3 ]
Piron, A. [4 ]
Delalleau, N. [1 ]
Pasquetti, G. [1 ]
Moreno Lopez, M. [1 ]
Gmyr, V. [1 ]
Cnop, M. [4 ]
Kerr-Conte, J. [1 ]
Pattou, F. [1 ]
Pontoglio, M. [3 ]
Liston, A. [2 ]
Bonner, C. [1 ]
机构：
[1] Univ Lille, CHU Lille, INSERM, Inst Pasteur, Lille, France
[2] KU Leuven VIB, Ctr Brain & Dis Res, Leuven, Belgium
[3] Inst Necker Enfants Malad, Paris, France
[4] ULB Ctr Diabet Res, Brussels, Belgium
来源：
DIABETOLOGIA | 2022年 / 65卷 / SUPPL 1期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
307
引用
收藏
页码：S161 / S161
页数：1
相关论文
共 50 条
  • [1] Treatment of young patients with HNF1A mutations (HNF1A-MODY)
    Raile, K.
    Schober, E.
    Konrad, K.
    Thon, A.
    Grulich-Henn, J.
    Meissner, T.
    Woelfle, J.
    Scheuing, N.
    Holl, R. W.
    DIABETIC MEDICINE, 2015, 32 (04) : 526 - 530
  • [2] Exploring sonic hedgehog signalling and HNF1A crosstalk in HNF1A-MODY stem cell islets
    Unger, L.
    Legoy, T.
    Chera, S.
    Ghila, L.
    DIABETOLOGIA, 2024, 67 : S209 - S209
  • [3] Half-Life of Sulfonylureas in HNF1A and HNF4A Human MODY Patients is not Prolonged as Suggested by the Mouse Hnf1a-/- Model
    Urbanova, Jana
    Andel, Michal
    Potockova, Jana
    Klima, Josef
    Macek, Jan
    Ptacek, Pavel
    Mat'oska, Vaclav
    Kumstyrova, Tereza
    Heneberg, Petr
    CURRENT PHARMACEUTICAL DESIGN, 2015, 21 (39) : 5736 - 5748
  • [4] A novel variant HNF1A gene (HNF1A-MODY) in a patient presenting with hyperglycaemia and glycosuria
    Bisbinas, Vasiliki
    Sertedaki, Amalia
    Giannopoulos, Andreas
    Karabouta, Zacharoula
    HORMONE RESEARCH IN PAEDIATRICS, 2021, 94 (SUPPL 1): : 256 - 256
  • [5] Double Heterozygous Mutations Involving Both HNF1A/MODY3 and HNF4A/MODY1 Genes
    Forlani, Gabriele
    Zucchini, Stefano
    Di Rocco, Antonio
    Di Luzio, Raffaella
    Scipione, Mirella
    Marasco, Elena
    Romeo, Giovanni
    Marchesini, Giulio
    Mantovani, Vilma
    DIABETES CARE, 2010, 33 (11) : 2336 - 2338
  • [6] GCK, HNF1A and HNF4A variant analysis in suspected MODY patients
    Zemeckiene, Zivile
    Sukys, Marius
    Jonikas, Rimvydas
    Nasvytiene, Inga
    Valanciute, Inga
    Poceviciene, Inga
    Ugenskiene, Rasa
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2022, 30 (SUPPL 1) : 148 - 149
  • [7] The Common HNF1A Variant I27L Is a Modifier of Age at Diabetes Diagnosis in Individuals With HNF1A-MODY
    Locke, Jonathan M.
    Saint-Martin, Cecile
    Laver, Thomas W.
    Patel, Kashyap A.
    Wood, Andrew R.
    Sharp, Seth A.
    Ellard, Sian
    Bellanne-Chantelot, Christine
    Hattersley, Andrew T.
    Harries, Lorna W.
    Weedon, Michael N.
    DIABETES, 2018, 67 (09) : 1903 - 1907
  • [8] MODY genes HNF1A, GCK and HNF4A pathogenic variant spectrum in pediatric patients
    Sukys, M.
    Asmoniene, V.
    Traberg, R.
    Cereskevicius, D.
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2019, 27 : 1262 - 1263
  • [9] HNF1A and HNF4A mutations are associated with prolonged half-life of glibenclamide but not glipizide in human MODY subjects
    Urbanova, J.
    Andel, M.
    DIABETOLOGIA, 2014, 57 : S327 - S327
  • [10] Novel Presentations of Congenital Hyperinsulinism due to Mutations in the MODY genes: HNF1A and HNF4A
    Stanescu, Diana E.
    Hughes, Nkecha
    Kaplan, Bernard
    Stanley, Charles A.
    De Leon, Diva D.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2012, 97 (10): : E2026 - E2030
12345