Two new metabolites with cytotoxicities from deep-sea fungus, Aspergillus sydowi YH11-2

被引：0
|
作者：
Li, De-Hai
Cai, Sheng-Xin
Tian, Li
Lin, Zhen-Jian
Zhu, Tian-Jiao
Fang, Yu-Chun
Liu, Pei-Pei
Gu, Qian-Qun [1 ]
Zhu, Wei-Ming
机构：
[1] Ocean Univ China, Inst Marine Drugs & Food, Chinese Minist Educ, Key Lab Marine Drugs, Qingdao 266003, Peoples R China
[2] Inst Oceanog 1, State Ocean Adm, Qingdao 266061, Peoples R China
来源：
ARCHIVES OF PHARMACAL RESEARCH | 2007年 / 30卷 / 09期
关键词：
Aspergillus sydowi; metabolite; cytotoxicities;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new compounds, 2, 3, 5-trimethyl-6-(3-oxobutan-2-yl)-4H-pyran-4-one (1) and (2R)-2, 3dihydro-7-hydroxy-6, 8-dimethyl-2-[(E)-prop-1-enyl] chromen-4-one (2), together with six known compounds (3-8), were isolated from a deep-sea fungus, identified as Aspergillus sydowi, by a bioassay-guided method. Their structures were elucidated by spectroscopic methods and the cytotoxicities were evaluated by SRB method.
引用
收藏
页码：1051 / 1054
页数：4
相关论文
共 50 条
  • [1] Two new metabolites with cytotoxicities from deep-sea fungus, aspergillus sydowi YH11-2
    Li Tian
    Sheng-Xin Cai
    De-Hai Li
    Zhen-Jian Lin
    Tian-Jiao Zhu
    Yu-Chun Fang
    Pei-Pei Liu
    Qian-Qun Gu
    Wei-Ming Zhu
    Archives of Pharmacal Research, 2007, 30 (9) : 1051 - 1054
  • [2] Secondary metabolites from the deep-sea derived fungus Aspergillus terreus MCCC M28183
    Huang, Xiaomei
    Wang, Yichao
    Li, Guangyu
    Shao, Zongze
    Xia, Jinmei
    Qin, Jiang-Jiang
    Wang, Weiyi
    FRONTIERS IN MICROBIOLOGY, 2024, 15
  • [3] Bioactive secondary metabolites from the deep-sea derived fungus Aspergillus sp. SCSIO 41029
    Chen, Weihao
    Chen, Chunmei
    Long, Jieyi
    Lan, Sujuan
    Lin, Xiuping
    Liao, Shengrong
    Yang, Bin
    Zhou, Xuefeng
    Wang, Junfeng
    Liu, Yonghong
    JOURNAL OF ANTIBIOTICS, 2021, 74 (02): : 156 - 159
  • [4] Bioactive secondary metabolites from the deep-sea derived fungus Aspergillus sp. SCSIO 41029
    Weihao Chen
    Chunmei Chen
    Jieyi Long
    Sujuan Lan
    Xiuping Lin
    Shengrong Liao
    Bin Yang
    Xuefeng Zhou
    Junfeng Wang
    Yonghong Liu
    The Journal of Antibiotics, 2021, 74 : 156 - 159
  • [5] Six New Antimicrobial Metabolites from the Deep-Sea Sediment-Derived Fungus Aspergillus fumigatus SD-406
    Yan, Li-Hong
    Li, Xiao-Ming
    Chi, Lu-Ping
    Li, Xin
    Wang, Bin-Gui
    MARINE DRUGS, 2022, 20 (01)
  • [6] 2 NEW METABOLITES, SYDONIC ACID AND HYDROXYSYDONIC ACID, FROM ASPERGILLUS-SYDOWI
    HAMASAKI, T
    NAGAYAMA, K
    HATSUDA, Y
    AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1978, 42 (01): : 37 - 40
  • [7] Nitrogen-Containing Secondary Metabolites from a Deep-Sea Fungus Aspergillus unguis and Their Anti-Inflammatory Activity
    Anh, Cao Van
    Yoon, Yeo Dae
    Kang, Jong Soon
    Lee, Hwa-Sun
    Heo, Chang-Su
    Shin, Hee Jae
    MARINE DRUGS, 2022, 20 (03)
  • [8] Acremolin D, a new acremolin alkaloid from the deep-sea sediment derived Aspergillus sydowii fungus
    Niu, Siwen
    Chen, Ziming
    Pei, Shengxiang
    Shao, Zongze
    Zhang, Gaiyun
    Hong, Bihong
    NATURAL PRODUCT RESEARCH, 2022, 36 (19) : 4936 - 4942
  • [9] Five New Indole Alkaloid Derivatives from Deep-Sea Fungus Aspergillus fumigatus AF1
    Dai, Lai-Hui
    Zhang, Gao-Rong
    Ou, Yang-Hui
    Liu, Xiao-Jing
    Yao, Hong-Liang
    Hu, Wen-Hao
    Li, Hou-Jin
    Lan, Wen-Jian
    MARINE DRUGS, 2025, 23 (01)
  • [10] Potential α-Glucosidase Inhibitors from the Deep-Sea Sediment-Derived Fungus Aspergillus insulicola
    Zhao, Weibo
    Zeng, Yanbo
    Chang, Wenjun
    Chen, Huiqin
    Wang, Hao
    Dai, Haofu
    Lv, Fang
    MARINE DRUGS, 2023, 21 (03)
12345