Lung transplantation for cystic fibrosis: Ten years of experience

被引：11

作者：

Aratari, M. T. ^{[1
]}

Venuta, F. ^{[1
]}

De Giacomo, T. ^{[1
]}

Rendina, E. A. ^{[1
]}

Anile, M. ^{[1
]}

Diso, D. ^{[1
]}

Francioni, F. ^{[1
]}

Quattrucci, S. ^{[1
]}

Rolla, M. ^{[1
]}

Pugliese, F. ^{[1
]}

Liparulo, V. ^{[1
]}

Di Stasio, M. ^{[1
]}

Ricella, C. ^{[1
]}

Tsagkaropoulos, S. ^{[1
]}

Ferretti, G. ^{[1
]}

Coloni, G. F. ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dept Thorac Surg, I-00161 Rome, Italy

来源：

TRANSPLANTATION PROCEEDINGS | 2008年 / 40卷 / 06期

关键词：

D O I：

10.1016/j.transproceed.2008.05.029

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Lung transplantation represents the only therapeutic option for patients affected by end-stage cystic fibrosis (CF). We performed 76 lung transplantations in 73 patients from 1996-2007. The mean time on the waiting list was 10 +/- 6 months. The median follow-up after the transplantation was 69.3 months. Twenty-one transplants (27.6%) were performed under cardiopulmonary bypass. Perioperative mortality, excluding retransplants, was 16.4% (12 patients) and the causes of death were sepsis, primary graft failure, and myocardial infarction. The overall survival was 74.5% +/- 5%, 62.9% +/- 5%, 54.1% +/- 6%, and 43.4% +/- 6% at 1, 3, 5, and 10 years, respectively. The accurate selection of potential recipients and the correct timing of referral and transplantation are factors that play crucial roles to obtain satisfactory results in term of improvement of quality of life and long-term survival.

引用

页码：2001 / 2002

页数：2

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