Carnitine Palmitoyltransferase (CPT) Modulators: A Medicinal Chemistry Perspective on 35 Years of Research

被引：86
|
作者：
Ceccarelli, Simona M. [1 ]
Chomienne, Odile [1 ]
Gubler, Marcel [1 ]
Arduini, Arduino [2 ]
机构：
[1] F Hoffmann La Roche Ltd, Div Pharmaceut, CH-4070 Basel, Switzerland
[2] CoreQuest Sagl, CH-6934 Bioggio, Switzerland
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 2011年 / 54卷 / 09期
关键词：
FATTY-ACID OXIDATION; PALMOXIRATE METHYL 2-TETRADECYLGLYCIDATE; PROLIFERATOR-ACTIVATED RECEPTOR; MALONYL-COA SENSITIVITY; ORAL HYPOGLYCEMIC AGENT; PALMITOYL TRANSFERASE-I; DECREASES FOOD-INTAKE; PERFUSED RAT HEARTS; N-TERMINAL DOMAIN; HEPATIC CARNITINE;
D O I：
10.1021/jm100809g
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：3109 / 3152
页数：44
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