Complexes derived from some biologically active ligands

Complexes derived from ampicillin (L1) and amoxicillin (L2) with (Mg(II), Ca(II), Zn(II), Cu(II), Ni(II), Co(II), Ce(III), Nd(III), UO2(VI), Th(IV)) were prepared and characterized by elemental analysis, electrical conductivity measurements, magnetic susceptibility, IR, UV/Vis, and thermogravimetry. The formed complexes can be formulated as (ML(H2O)(3)(NO3)(n)) except for Ce(III) which gave (CeL(H2O)(3)(Cl)(2)). The H-1 NMR spectra of the Zn(II) complexes are compared to spectra of the ligands. The shift (delta) gave information about the chelating center of the ligands. The ligands and the synthesized complexes, derived from some alkali earth and transition metal ions, were tested as antibacterial reagents. The formed complexes had enhanced activity.