Ph3P/I--Promoted Dichlorination or Dibromination of Epoxides with XCH2CH2X (X = Cl or Br)

被引：4

作者：

Long, Jin ^{[1
,2
]}

Chen, Jia ^{[2
]}

Li, Rong ^{[1
]}

Liu, Zhuo ^{[1
,2
]}

Xiao, Xuan ^{[1
,2
]}

Lin, Jin-Hong ^{[2
]}

Zheng, Xing ^{[1
]}

Xiao, Ji-Chang ^{[2
]}

机构：

[1] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Inst Pharm & Pharmacol, 28 Western Changsheng Rd, Hengyang 421001, Hunan, Peoples R China

[2] Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China

来源：

SYNLETT | 2019年 / 30卷 / 02期

关键词：

epoxide; dichlorination; dibromination; 1,2-dihalides; triphenylphosphine; VIC-HALO ALCOHOLS; VICINAL DIHALIDES; PHOSPHONIUM SALT; TRIPHENYLPHOSPHINE; HALOGENATION; REAGENT; STEREOCHEMISTRY; CHLORINATION; DEHYDRATION; CONVERSION;

D O I：

10.1055/s-0037-1610308

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ph3P/I--promoted dichlorination and dibromination of epoxides by using XCH2CH2X (X = Cl or Br) as the halogen source and reaction solvent is described. All reagents are widely available and easy to handle, and mild conditions and operational simplicity make this protocol attractive.

引用

页码：181 / 184

页数：4

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