Convenient Synthesis of 2-Amino-4H-chromenes from Photochemically Generated o-Quinone Methides and Malononitrile

被引：18

作者：

Fujiwara, Makoto ^{[1
]}

Sakamoto, Masanori ^{[1
]}

Komeyama, Kimihiro ^{[1
]}

Yoshida, Hiroto ^{[1
]}

Takaki, Ken ^{[1
]}

机构：

[1] Hiroshima Univ, Grad Sch Engn, Dept Appl Chem, Higashihiroshima 7398527, Japan

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2015年 / 52卷 / 01期

关键词：

AQUEOUS-MEDIA; MANNICH-BASES; 2-AMINO-2-CHROMENES; DERIVATIVES;

D O I：

10.1002/jhet.1964

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Amino-4H-chromenes were synthesized in moderate to good yields by the reaction of o-quinone methides photochemically generated from o-(dimethylaminomethyl)phenols with malononitrile. This method was applicable to the synthesis of fluorinated chromenes that were difficult to obtain by other methods. In addition, o-(hydroxymethyl)phenols could be used for the reaction in the presence of tertiary amine bases.

引用

页码：59 / 66

页数：8

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