Preparation of a C2-symmetric binol-derived diol and its application in the catalytic enantioselective and catalyst-controlled diastereoselective allylboration of aldehydes

被引：22
|
作者：
Rauniyar, Vivek [1 ]
Hall, Dennis G. [1 ]
机构：
[1] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada
来源：
SYNTHESIS-STUTTGART | 2007年 / 21期
关键词：
allylboration; Bronsted acid; enantioselective catalysis; chiral diol; propionate units;
D O I：
10.1055/s-2007-983832
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel C-2-symmetric Binol-derived diol is described. It is readily applicable towards combined acid catalysis for the asymmetric allylboration of aldehydes to provide homoallylic alcohols in high enantioselectivities, and dictates the diastereoselectivity in the reaction of an achiral allylboronate with chiral aldehydes.
引用
收藏
页码：3421 / 3426
页数：6
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