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Efficacy of a psychological online intervention for depression in people with epilepsy: A randomized controlled trial
被引:82
|作者:
Schroeder, Johanna
[1
]
Brueckner, Katja
[2
]
Fischer, Anja
[3
]
Lindenau, Matthias
[2
]
Koether, Ulf
[1
]
Vettorazzi, Eik
[4
]
Moritz, Steffen
[1
]
机构:
[1] Univ Med Ctr Hamburg Eppendorf, Dept Psychiat & Psychotherapy, D-20246 Hamburg, Germany
[2] Protestant Hosp Hamburg Alsterdorf, Dept Neurol & Epileptol, Hamburg, Germany
[3] Univ Med Ctr Hamburg Eppendorf, Ctr Mol Neurobiol, D-20246 Hamburg, Germany
[4] Univ Med Ctr Hamburg Eppendorf, Dept Med Biometry & Epidemiol, D-20246 Hamburg, Germany
来源:
关键词:
Depression;
Epilepsy;
Internet intervention;
iCBT;
Deprexis;
QUALITY-OF-LIFE;
PSYCHOMETRIC PROPERTIES;
PSYCHOTHERAPY-RESEARCH;
METAANALYSIS;
INTERNET;
INVENTORY;
THERAPY;
STIGMA;
BURDEN;
BECK;
D O I:
10.1111/epi.12833
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
ObjectiveDepression is the most prevalent psychiatric disorder in persons with epilepsy (PWEs). Despite its major impact on quality of life and risk of suicide, most PWEs are not treated for depression. A current challenge in mental health care is how to close this treatment gap and increase access to psychological services. Psychological online interventions (POIs) have shown efficacy in improving depression among individuals without neurologic disorders. This pilot study aimed to assess the feasibility and efficacy of a psychological online intervention for depression (Deprexis) in PWEs who have symptoms of depression. MethodsParticipants with self-reported epilepsy and subjective complaints of depressive symptoms were randomized to an intervention condition (Deprexis) or to a waiting list control (WLC) condition. After 9weeks, participants were invited to complete an online reassessment. ResultsRelative to the waiting list group, program users experienced a significant symptom decline on the Beck Depression Inventory - I (BDI-I, primary outcome) with a moderate effect size in the complete observations analysis and a small effect size in the intention-to-treat analysis. Furthermore, there was a significant improvement with a moderate effect size on the energy/fatigue subscale of the Quality of Life In Epilepsy Inventory - 31 (QOLIE-31). SignificanceThe results of this trial suggest that POIs may be a feasible and beneficial tool for PWEs who have comorbid depressive symptoms.
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页码:2069 / 2076
页数:8
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