Surface-functionalized silica-coated gold nanoparticles and their bioapplications

被引:37
|
作者
Liu, SH
Zhang, ZH
Wang, YB
Wang, FK
Han, MY
机构
[1] Inst Mat Res & Engn, Singapore 117602, Singapore
[2] Div Bioengn, Singapore 117602, Singapore
关键词
gold nanoparticles; silica coating; surface functionalization; bioconjugation;
D O I
10.1016/j.talanta.2005.06.020
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Monodisperse Au at SiO2 nanoparticles has been functionalized with carboxylic groups for further bioconjugation with amino-terminated oligonucleotides. The oligonucleotide-modified Au at SiO2 nanoprobes have been applied in the fast colorimetric DNA based on the sequence-specific hybridization properties of DNA. Self-assembling behavior of Au at SiO2 nanoparticles was also investigated. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:456 / 461
页数:6
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