Research Progress of the Types and Preparation Techniques of Scaffold Materials in Cartilage Tissue Engineering

被引：20

作者：

Fu, Na ^{[2
]}

Dong, Tengzhe ^{[2
]}

Meng, Ai ^{[2
]}

Meng, Zhaosong ^{[2
]}

Zhu, Bofeng ^{[3
,4
]}

Lin, Yunfeng ^{[1
]}

机构：

[1] Sichuan Univ, West China Hosp Stomatol, State Key Lab Oral Dis, Chengdu 610041, Sichuan, Peoples R China

[2] Tianjin Med Univ, Sch Stomatol, Hosp Stomatol, Tianjin, Peoples R China

[3] Xi An Jiao Tong Univ, Coll Stomatol, Key Lab Shaanxi Prov Craniofacial Precis Med Res, Xian, Shaanxi, Peoples R China

[4] Xi An Jiao Tong Univ, Coll Stomatol, Clin Res Ctr Shaanxi Prov Dent & Maxillofacial Di, Xian, Shaanxi, Peoples R China

来源：

CURRENT STEM CELL RESEARCH & THERAPY | 2018年 / 13卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Chondral defect; cartilage tissue engineering; scaffold; scaffold materials; scaffold fabrication technology; collagen; TUNABLE MECHANICAL-PROPERTIES; STEM-CELLS; ARTICULAR-CARTILAGE; POROUS SCAFFOLDS; 3-DIMENSIONAL SCAFFOLDS; MICROBIAL SYNTHESIS; COMPOSITE SCAFFOLD; MENISCUS REPAIR; OXYGEN-TENSION; GROWTH-FACTORS;

D O I：

10.2174/1574888X12666170718152611

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

The management of chondral defects has been a challenge for a long time because of the poor self-healing capacity of articular cartilage. Many approaches ranging from symptomatic treatment to structural cartilage regeneration are not that successful with very limited satisfactory results. Chondral defects caused by tumor, trauma, infection, congenital malformations are very common in clinical trials. It seriously affects the patient's physical function and quality of life. The appearance of cartilage tissue engineering has brought good news for cartilage defect repair. Through this review, we are aimed at reviewing the progress of the types and preparation techniques of scaffold materials in cartilage tissue engineering.

引用

页码：583 / 590

页数：8

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